Therapeutic Peptide Database

Search TPDB peptide records

Query curated peptide sequences, activity labels, length ranges, and database provenance.

Antibacterial Anticancer Antiviral 5-20 aa REST API
TPDB database overview showing data curation, evidence records, structures, website interface, and benchmark resources

Dataset snapshot

131347
activity endpoints
88277
peptides
24
activity types
72
sources
6876
max length

Activity category statistics

10 functional classes
Anti-infective peptides 53920
Antibacterial 26758 Antiviral 6681 Antifungal 13478 Antiparasitic 6542 Quorum sensing 461
Cardiometabolic peptides 5427
ACE inhibitors 1885 Antihypertensive 1876 Antidiabetic 971 iDPPIV 695
Cancer-related peptides 14722
Anticancer 12464 Tumor T cell antigens 576 Tumor-homing Peptides 1682
Immunity and inflammation peptides 3908
Anti-inflammatory 3908
Toxicity and safety peptides 28229
Hemolysis 2421 Toxicity 23710 Neurotoxin 2098
Delivery and barrier-penetrating peptides 6763
Cell-penetrating Peptides 5566 Blood-Brain Barrier 1197
Neuroactive peptides 10846
Neuropeptide 10846
Food sensory peptides 1104
Bitter 444 Umami 660
Functional / health-promoting peptides 2344
Antioxidant 2344
Environmental / surface-functional peptides 3600
Antifouling 3600
Self-assembling and biomaterial peptides 484
Selfassembly 484

External resources

Related databases

Official links

Example records

LL-37 3D structure thumbnail LL-37 TPDB01088 37 aa Magainin 2 3D structure thumbnail Magainin 2 TPDB00615 23 aa Melittin 3D structure thumbnail Melittin TPDB05085 26 aa Nisin Z 3D structure thumbnail Nisin Z TPDB04540 34 aa Pexiganan / MSI-78 3D structure thumbnail Pexiganan / MSI-78 TPDB84089 22 aa Aurein 2.1 3D structure thumbnail Aurein 2.1 TPDB03946 16 aa Apamin 3D structure thumbnail Apamin TPDB29201 18 aa Bradykinin 3D structure thumbnail Bradykinin TPDB01628 9 aa Cecropin A derivative 3D structure thumbnail Cecropin A derivative TPDB03501 37 aa Phylloseptin 3D structure thumbnail Phylloseptin TPDB02326 32 aa

Fielded search

Search ID and sequence, then refine by activity, category, source, and length.

Structured records

Open a TPDB ID to inspect sequence, activity labels, provenance, and FASTA output.

Export and API

Download filtered CSV files or query the JSON endpoint from scripts and notebooks.