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Peptide record

TPDB03946

Aurein 2.1 Antibacterial Anticancer Antifungal Antiparasitic standard
16 amino acids
Basic Information
3D PDB MODEL
Drag to rotate. Click a residue or atom to inspect it; the selected residue is highlighted in amber.
TPDB03946
Aurein 2.1
Antibacterial Anticancer Antifungal Antiparasitic
Anti-infective peptides Cancer-related peptides
AntiBP3 dbAMP Peptipedia ACP740 _ACP240 AntiCP 2.0 CancerPPD 2.0 SATPdb dbACP iACP-DRLF pep-lab AFP-GFuse Antifp Antifungipept CAFPdb i2APP
standard
No
A 16-aa standard natural multi-activity (Antibacterial, Anticancer, Antifungal, and other sources) peptide sequence curated from AntiBP3, dbAMP, Peptipedia, and other sources, with an available 3D structural model.
Sequence
GLLDIVKKVVGAFGSL
Physicochemical Analysis
C76H130N18O20
RNCEQHMPTWY
GLV
1615.98
9.88
2
1
9
+1
0.29
1.237
158.12
Mammalian: 30 hour Yeast: >20 hour E.coli: >10 hour
0
0.00
1
Residue Composition
number
1
A
0
R
0
N
1
D
0
C
0
E
0
Q
3
G
0
H
1
I
3
L
2
K
0
M
1
F
0
P
1
S
0
T
0
W
0
Y
3
V
Amino Acid Distribution
A: 1 R: 0 N: 0 D: 1 C: 0 E: 0 Q: 0 G: 3 H: 0 I: 1 L: 3 K: 2 M: 0 F: 1 P: 0 S: 1 T: 0 W: 0 Y: 0 V: 3
Chemical Descriptors
16
C76H130N18O20
1615.98
9.88
+1
0.29
1.237
Free
L
Not Available
Free
Anticancer
Southern bell frogLitoria aureaorLitoria raniformis, Australia
Evidence Records 22 records
Evidence 1 Activity

Activity

MIC
Antibacterial
50 µg/mL

Target

B. cereus

Source & Reference

dbAMP

Other

Source Activity Label Source Definition
Antibacterial
dbAMP classified as Antibacterial under the Anti-bacterial function class.
Active against B. cereus (MIC 50 ug/ml), E.coli (MIC >100 ug/ml), L. lactis (MIC 6 ug/ml), L. innocua (MIC 6 ug/ml), M. luteus (M
Evidence 2 Activity

Activity

MIC
Antibacterial
>100 µg/mL

Target

E.coli

Source & Reference

dbAMP

Other

Active against B. cereus (MIC 50 ug/ml), E.coli (MIC >100 ug/ml), L. lactis (MIC 6 ug/ml), L. innocua (MIC 6 ug/ml), M. luteus (MIC 100 ug/ml), P.multocid
Evidence 3 Activity

Activity

MIC
Antibacterial
6 µg/mL

Target

L. lactis

Source & Reference

dbAMP

Other

Active against B. cereus (MIC 50 ug/ml), E.coli (MIC >100 ug/ml), L. lactis (MIC 6 ug/ml), L. innocua (MIC 6 ug/ml), M. luteus (MIC 100 ug/ml), P.multocida (MIC > 100 ug/ml), S.au
Evidence 4 Activity

Activity

MIC
Antibacterial
6 µg/mL

Target

L. innocua

Source & Reference

dbAMP

Other

ctive against B. cereus (MIC 50 ug/ml), E.coli (MIC >100 ug/ml), L. lactis (MIC 6 ug/ml), L. innocua (MIC 6 ug/ml), M. luteus (MIC 100 ug/ml), P.multocida (MIC > 100 ug/ml), S.aureus (MIC > 100 ug/ml), S.
Evidence 5 Activity

Activity

MIC
Antibacterial
100 µg/mL

Target

M. luteus

Source & Reference

dbAMP

Other

IC 50 ug/ml), E.coli (MIC >100 ug/ml), L. lactis (MIC 6 ug/ml), L. innocua (MIC 6 ug/ml), M. luteus (MIC 100 ug/ml), P.multocida (MIC > 100 ug/ml), S.aureus (MIC > 100 ug/ml), S. epidermidis (MIC 50 ug/ml)
Evidence 6 Activity

Activity

MIC
Antibacterial
50 µg/mL

Target

Staphylococcus epidermidis

Source & Reference

dbAMP

Other

l), M. luteus (MIC 100 ug/ml), P.multocida (MIC > 100 ug/ml), S.aureus (MIC > 100 ug/ml), S. epidermidis (MIC 50 ug/ml), and S. uberis (MIC 100 ug/ml) (provided by Chunfeng Wang, validated GW). Contains: Aurei
Evidence 7 Activity

Activity

MIC
Antibacterial
100 µg/mL

Target

S. uberis

Source & Reference

dbAMP

Other

ltocida (MIC > 100 ug/ml), S.aureus (MIC > 100 ug/ml), S. epidermidis (MIC 50 ug/ml), and S. uberis (MIC 100 ug/ml) (provided by Chunfeng Wang, validated GW). Contains: Aurein 2.1.1 (residue 3 to 16)
Evidence 8 Activity

Activity

Not Available
Anticancer

Target

Not Available
Not Available
Not Available

Assay & Model

Not Available
Not Available

Source & Reference

CancerPPD 2.0 dbACP SATPdb
CancerPPD2
2000

Other

Source Activity Label Source Definition
Anticancer
CancerPPD 2.0 manually curated experimentally verified anticancer peptide/protein annotation.
Evidence 9 Activity

Activity

MIC
Antifungal
50 µg/mL

Target

B. cereus

Source & Reference

dbAMP CAFPdb Antifungipept

Other

Source Activity Label Source Definition
Antifungal
dbAMP classified under the Anti-fungal function class.
Active against B. cereus (MIC 50 ug/ml), E.coli (MIC >100 ug/ml), L. lactis (MIC 6 ug/ml), L. innocua (MIC 6 ug/ml), M. luteus (M
Evidence 10 Activity

Activity

MIC
Antifungal
>100 µg/mL

Target

E.coli

Source & Reference

dbAMP CAFPdb Antifungipept

Other

Active against B. cereus (MIC 50 ug/ml), E.coli (MIC >100 ug/ml), L. lactis (MIC 6 ug/ml), L. innocua (MIC 6 ug/ml), M. luteus (MIC 100 ug/ml), P.multocid
Evidence 11 Activity

Activity

MIC
Antifungal
6 µg/mL

Target

L. lactis

Source & Reference

dbAMP CAFPdb Antifungipept

Other

Active against B. cereus (MIC 50 ug/ml), E.coli (MIC >100 ug/ml), L. lactis (MIC 6 ug/ml), L. innocua (MIC 6 ug/ml), M. luteus (MIC 100 ug/ml), P.multocida (MIC > 100 ug/ml), S.au
Evidence 12 Activity

Activity

MIC
Antifungal
6 µg/mL

Target

L. innocua

Source & Reference

dbAMP CAFPdb Antifungipept

Other

ctive against B. cereus (MIC 50 ug/ml), E.coli (MIC >100 ug/ml), L. lactis (MIC 6 ug/ml), L. innocua (MIC 6 ug/ml), M. luteus (MIC 100 ug/ml), P.multocida (MIC > 100 ug/ml), S.aureus (MIC > 100 ug/ml), S.
Evidence 13 Activity

Activity

MIC
Antifungal
100 µg/mL

Target

M. luteus

Source & Reference

dbAMP CAFPdb Antifungipept

Other

IC 50 ug/ml), E.coli (MIC >100 ug/ml), L. lactis (MIC 6 ug/ml), L. innocua (MIC 6 ug/ml), M. luteus (MIC 100 ug/ml), P.multocida (MIC > 100 ug/ml), S.aureus (MIC > 100 ug/ml), S. epidermidis (MIC 50 ug/ml)
Evidence 14 Activity

Activity

MIC
Antifungal
50 µg/mL

Target

Staphylococcus epidermidis

Source & Reference

dbAMP CAFPdb Antifungipept

Other

l), M. luteus (MIC 100 ug/ml), P.multocida (MIC > 100 ug/ml), S.aureus (MIC > 100 ug/ml), S. epidermidis (MIC 50 ug/ml), and S. uberis (MIC 100 ug/ml) (provided by Chunfeng Wang, validated GW). Contains: Aurei
Evidence 15 Activity

Activity

MIC
Antifungal
100 µg/mL

Target

S. uberis

Source & Reference

dbAMP CAFPdb Antifungipept

Other

ltocida (MIC > 100 ug/ml), S.aureus (MIC > 100 ug/ml), S. epidermidis (MIC 50 ug/ml), and S. uberis (MIC 100 ug/ml) (provided by Chunfeng Wang, validated GW). Contains: Aurein 2.1.1 (residue 3 to 16)
Evidence 16 Activity

Activity

MIC
Antiparasitic
50 µg/mL

Target

B. cereus

Source & Reference

NA

Other

Active against B. cereus (MIC 50 ug/ml), E.coli (MIC >100 ug/ml), L. lactis (MIC 6 ug/ml), L. innocua (MIC 6 ug/ml), M. luteus (M
Evidence 17 Activity

Activity

MIC
Antiparasitic
>100 µg/mL

Target

E.coli

Source & Reference

NA

Other

Active against B. cereus (MIC 50 ug/ml), E.coli (MIC >100 ug/ml), L. lactis (MIC 6 ug/ml), L. innocua (MIC 6 ug/ml), M. luteus (MIC 100 ug/ml), P.multocid
Evidence 18 Activity

Activity

MIC
Antiparasitic
6 µg/mL

Target

L. lactis

Source & Reference

NA

Other

Active against B. cereus (MIC 50 ug/ml), E.coli (MIC >100 ug/ml), L. lactis (MIC 6 ug/ml), L. innocua (MIC 6 ug/ml), M. luteus (MIC 100 ug/ml), P.multocida (MIC > 100 ug/ml), S.au
Evidence 19 Activity

Activity

MIC
Antiparasitic
6 µg/mL

Target

L. innocua

Source & Reference

NA

Other

ctive against B. cereus (MIC 50 ug/ml), E.coli (MIC >100 ug/ml), L. lactis (MIC 6 ug/ml), L. innocua (MIC 6 ug/ml), M. luteus (MIC 100 ug/ml), P.multocida (MIC > 100 ug/ml), S.aureus (MIC > 100 ug/ml), S.
Evidence 20 Activity

Activity

MIC
Antiparasitic
100 µg/mL

Target

M. luteus

Source & Reference

NA

Other

IC 50 ug/ml), E.coli (MIC >100 ug/ml), L. lactis (MIC 6 ug/ml), L. innocua (MIC 6 ug/ml), M. luteus (MIC 100 ug/ml), P.multocida (MIC > 100 ug/ml), S.aureus (MIC > 100 ug/ml), S. epidermidis (MIC 50 ug/ml)
Evidence 21 Activity

Activity

MIC
Antiparasitic
50 µg/mL

Target

Staphylococcus epidermidis

Source & Reference

NA

Other

l), M. luteus (MIC 100 ug/ml), P.multocida (MIC > 100 ug/ml), S.aureus (MIC > 100 ug/ml), S. epidermidis (MIC 50 ug/ml), and S. uberis (MIC 100 ug/ml) (provided by Chunfeng Wang, validated GW). Contains: Aurei
Evidence 22 Activity

Activity

MIC
Antiparasitic
100 µg/mL

Target

S. uberis

Source & Reference

NA

Other

ltocida (MIC > 100 ug/ml), S.aureus (MIC > 100 ug/ml), S. epidermidis (MIC 50 ug/ml), and S. uberis (MIC 100 ug/ml) (provided by Chunfeng Wang, validated GW). Contains: Aurein 2.1.1 (residue 3 to 16)