Back to search

Peptide record

TPDB93340

[D-Al Deltorphin II Blood-Brain Barrier modified_plain modified
11 amino acids
Basic Information
TPDB93340
[D-Al Deltorphin II
Blood-Brain Barrier
Delivery and barrier-penetrating peptides
Peptipedia
modified_plain
Yes
A 11-aa modified blood-brain barrier peptide sequence curated from Peptipedia, without an available 3D structural model.
C-terminal: Amidation C-terminal: Chemical modification N-terminal: C-terminal modification
Sequence
YaFEVVG-NH2
Physicochemical Analysis
C48H66N12O14
RDCQILKMPSTW
V
1035.12
5.13
1
1
5
-1
1.31
0.100
61.82
Mammalian: 2.8 hour Yeast: 10 min E.coli: 2 min
1490
143.94
2
Residue Composition
number
1
A
0
R
1
N
0
D
0
C
1
E
0
Q
1
G
1
H
0
I
0
L
0
K
0
M
1
F
0
P
0
S
0
T
0
W
1
Y
2
V
Amino Acid Distribution
A: 1 R: 0 N: 1 D: 0 C: 0 E: 1 Q: 0 G: 1 H: 1 I: 0 L: 0 K: 0 M: 0 F: 1 P: 0 S: 0 T: 0 W: 0 Y: 1 V: 2
Chemical Descriptors
11
C48H66N12O14
1035.12
5.13
-1
1.31
0.100
Chemical modification
Linear
C-terminal modification
Similarity
Tyr-(D)Ala-Phe-Glu-Val-Val-Gly-NH2
O=C(N)CNC(=O)C(NC(=O)C(NC(=O)C(NC(=O)C(NC(=O)C(NC(=O)C(N)Cc1ccc(O)cc1)C)Cc2ccccc2)CCC(=O)O)C(C)C)C(C)C
Evidence Records 1 records
Evidence 1 Activity

Activity

Blood-Brain Barrier
0.00003915 cm/s

Assay & Model

BMEC
Origin/Source
Permeability coefficient

Source & Reference

NA
B3Pdb

Other

human,mouse,rat
BMEC
(saturable)
Additional Detail Fields 1 fields
BMEC