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Peptide record

TPDB93333

LSZ 62 Blood-Brain Barrier modified_plain modified
21 amino acids
Basic Information
TPDB93333
LSZ 62
Blood-Brain Barrier
Delivery and barrier-penetrating peptides
Peptipedia
modified_plain
Yes
A 21-aa modified blood-brain barrier peptide sequence curated from Peptipedia, without an available 3D structural model.
C-terminal: Amidation Chemical: (D)Cys2-(D)Cys5
Sequence
YcGFc-(α-D-Glc)SG-NH2
Physicochemical Analysis
C56H78N16O19S3
AREQIKMPTWV
CG
1375.51
4.93
1
1
3
-1
-0.58
0.029
18.57
Mammalian: 2.8 hour Yeast: 10 min E.coli: 2 min
1615
117.41
6
Residue Composition
number
0
A
0
R
1
N
1
D
3
C
0
E
0
Q
3
G
1
H
0
I
1
L
0
K
0
M
1
F
0
P
1
S
0
T
0
W
1
Y
0
V
Amino Acid Distribution
A: 0 R: 0 N: 1 D: 1 C: 3 E: 0 Q: 0 G: 3 H: 1 I: 0 L: 1 K: 0 M: 0 F: 1 P: 0 S: 1 T: 0 W: 0 Y: 1 V: 0
Chemical Descriptors
21
C56H78N16O19S3
1375.51
4.93
-1
-0.58
0.029
(D)Cys2-(D)Cys5
Linear
Similarity
Tyr-(D)Cys-Gly-Phe-(D)Cys-(α-D-Glucose)Ser-Gly-NH2
O=C(N)CNC(=O)[C@@H](NC(=O)[C@H]2NC(=O)[C@@H](NC(=O)CNC(=O)[C@H](NC(=O)[C@@H](N)Cc1ccc(O)cc1)CSSC2)Cc3ccccc3)CO[C@H]4OC(CO)[C@H](O)C(O)[C@@H]4O
Evidence Records 1 records
Evidence 1 Activity

Activity

Blood-Brain Barrier
-1.161

Assay & Model

Shake Flask
Origin/Source
Log D

Source & Reference

NA
B3Pdb

Other

Chemically synthesized
Direct iodination