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Peptide record

TPDB93332

Agouti-related prote Blood-Brain Barrier modified_plain modified
54 amino acids
Basic Information
TPDB93332
Agouti-related prote
Blood-Brain Barrier
Delivery and barrier-penetrating peptides
Peptipedia
modified_plain
Yes
A 54-aa modified blood-brain barrier peptide sequence curated from Peptipedia, without an available 3D structural model.
C-terminal: Amidation Chemical: Cys5-Cys20, Cys12-Cys26, Cys19-Cys37, Cys23-Cys47,
Sequence
SSRRCVRLHESCLGQQVPCCDPCATCYCRFFNAFCYCRKLGTAMNPCSRT-NH2
Physicochemical Analysis
C245H384N80O71S11
IW
C
5938.90
8.32
9
2
14
+5
5.80
-0.274
37.96
Mammalian: 1.9 hour Yeast: >20 hour E.coli: >10 hour
3605
60.70
24
Residue Composition
number
3
A
6
R
3
N
1
D
10
C
1
E
2
Q
2
G
2
H
0
I
3
L
1
K
1
M
3
F
3
P
4
S
3
T
0
W
2
Y
2
V
Amino Acid Distribution
A: 3 R: 6 N: 3 D: 1 C: 10 E: 1 Q: 2 G: 2 H: 2 I: 0 L: 3 K: 1 M: 1 F: 3 P: 3 S: 4 T: 3 W: 0 Y: 2 V: 2
Chemical Descriptors
54
C245H384N80O71S11
5938.90
8.32
+5
5.80
-0.274
Cys5-Cys20, Cys12-Cys26, Cys19-Cys37, Cys23-Cys47,
Linear
Similarity
Ser-Ser-Arg-Arg-Cys-Val-Arg-Leu-His-Glu-Ser-Cys-Leu-Gly-Gln-Gln-Val-Pro-Cys-Cys-Asp-Pro-Cys-Ala-Thr-Cys-Tyr-Cys-Arg-Phe-Phe-Asn-Ala-Phe-Cys-Tyr-Cys-Arg-Lys-Leu-Gly-Thr-Ala-Met-Asn-Pro-Cys-Ser-Arg-Thr-NH2
Evidence Records 1 records
Evidence 1 Activity

Activity

Blood-Brain Barrier
-1.96

Assay & Model

Shake Flask
Origin/Source
Log P

Source & Reference

NA
B3Pdb

Other

Chemically synthesized
Direct iodination