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Peptide record

TPDB93325

Tumor-homing Peptides standard
7 amino acids
Basic Information
3D PDB MODEL
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TPDB93325
Tumor-homing Peptides
Cancer-related peptides
TumorHoPe2.0
standard
No
A 7-aa standard natural tumor-homing peptides peptide sequence curated from TumorHoPe2.0, with an available 3D structural model.
C-terminal: Amidation
Sequence
VNTANST-NH2
Physicochemical Analysis
C27H47N9O13
RDCEQGHILKMFPWY
NT
705.72
6.02
0
0
2
-0
1.15
-0.457
55.71
Mammalian: 100 hour Yeast: >20 hour E.coli: >10 hour
0
0.00
5
Residue Composition
number
1
A
0
R
2
N
0
D
0
C
0
E
0
Q
0
G
0
H
0
I
0
L
0
K
0
M
0
F
0
P
1
S
2
T
0
W
0
Y
1
V
Amino Acid Distribution
A: 1 R: 0 N: 2 D: 0 C: 0 E: 0 Q: 0 G: 0 H: 0 I: 0 L: 0 K: 0 M: 0 F: 0 P: 0 S: 1 T: 2 W: 0 Y: 0 V: 1
Chemical Descriptors
7
C27H47N9O13
705.72
6.02
-0
1.15
-0.457
Amide
Evidence Records 1 records
Evidence 1 Activity

Activity

Tumor-homing Peptides

Target

Tumor cell
Homing
Breast cancer, Squamous cell carcinoma, Colon carcinoma
vimentin

Source & Reference

TumorHoPe2.0
TumorHoPe2
Carcinoma homing peptide (CHP), its analogs, and methods of using
2017
US 9657077 B2
US 9657077 B2

Other

Source Activity Label Source Definition
Tumor-homing Peptides
TumorHoPe2.0 experimentally validated tumor-homing peptide annotation.
SCCVII, CT26, 4T1, and B16F10 cell line
C57B1/6 mice, C3H mice, Nude mice, wtIL-12−/− mice, female Balb/c mice (all are six to eight weeks old)
Phage Display library
interleukin 12 (IL-12)
Linear
Additional Detail Fields 3 fields
interleukin 12 (IL-12)
SCCVII, CT26, 4T1, and B16F10 cell line
C57B1/6 mice, C3H mice, Nude mice, wtIL-12−/− mice, female Balb/c mice (all are six to eight weeks old)