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Peptide record

TPDB93324

Peptide5 Tumor-homing Peptides standard
15 amino acids
Basic Information
3D PDB MODEL
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TPDB93324
Peptide5
Tumor-homing Peptides
Cancer-related peptides
TumorHoPe2.0
standard
No
A 15-aa standard natural tumor-homing peptides peptide sequence curated from TumorHoPe2.0, with an available 3D structural model.
C-terminal: tagged with AuNRs
Sequence
RTLIRMGTGAHAFAV
Physicochemical Analysis
C70H117N23O18S1
NDCEQKPSWY
A
1600.90
12.40
3
0
8
+2
0.21
0.547
91.33
Mammalian: 1 hour Yeast: 2 min E.coli: 2 min
0
0.00
2
Residue Composition
number
3
A
2
R
0
N
0
D
0
C
0
E
0
Q
2
G
1
H
1
I
1
L
0
K
1
M
1
F
0
P
0
S
2
T
0
W
0
Y
1
V
Amino Acid Distribution
A: 3 R: 2 N: 0 D: 0 C: 0 E: 0 Q: 0 G: 2 H: 1 I: 1 L: 1 K: 0 M: 1 F: 1 P: 0 S: 0 T: 2 W: 0 Y: 0 V: 1
Chemical Descriptors
15
C70H117N23O18S1
1600.90
12.40
+2
0.21
0.547
tagged with AuNRs
Evidence Records 1 records
Evidence 1 Activity

Activity

Tumor-homing Peptides

Target

Tumor cell
Targeting
Breast cancer

Source & Reference

TumorHoPe2.0
TumorHoPe2
Guiding nanomaterials to tumors for breast cancer precision medicine: from tumor-targeting small-molecule discovery to targeted nanodrug delivery
2017
Xuewei Qu et al. NPG Asia Mater. 2017:9:e452.

Other

Source Activity Label Source Definition
Tumor-homing Peptides
TumorHoPe2.0 experimentally validated tumor-homing peptide annotation.
MCF-7 human breast cancer cells
Athymic Nude-Foxn1nu mice (female, 3–5 weeks old)
Phage display library
f3-15mer phage library
Gold nanorods (AuNRs)
Additional Detail Fields 4 fields
Gold nanorods (AuNRs)
MCF-7 human breast cancer cells
Athymic Nude-Foxn1nu mice (female, 3–5 weeks old)
f3-15mer phage library