Back to search

Peptide record

TPDB93323

TZ14011 Tumor-homing Peptides standard
12 amino acids
Basic Information
3D PDB MODEL
Drag to rotate. Click a residue or atom to inspect it; the selected residue is highlighted in amber.
TPDB93323
TZ14011
Tumor-homing Peptides
Cancer-related peptides
TumorHoPe2.0
standard
No
A 12-aa standard natural tumor-homing peptides peptide sequence curated from TumorHoPe2.0, with an available 3D structural model.
N-terminal: acetylated
Sequence
RRACYKKPYRCR
Physicochemical Analysis
C68H114N26O15S2
NDEQGHILMFSTWV
R
1599.94
10.78
6
0
3
+6
3.14
-1.933
8.33
Mammalian: 1 hour Yeast: 2 min E.coli: 2 min
3105
194.07
4
Residue Composition
number
1
A
4
R
0
N
0
D
2
C
0
E
0
Q
0
G
0
H
0
I
0
L
2
K
0
M
0
F
1
P
0
S
0
T
0
W
2
Y
0
V
Amino Acid Distribution
A: 1 R: 4 N: 0 D: 0 C: 2 E: 0 Q: 0 G: 0 H: 0 I: 0 L: 0 K: 2 M: 0 F: 0 P: 1 S: 0 T: 0 W: 0 Y: 2 V: 0
Chemical Descriptors
12
C68H114N26O15S2
1599.94
10.78
+6
3.14
-1.933
acetylated
Evidence Records 1 records
Evidence 1 Activity

Activity

Tumor-homing Peptides

Target

T-lymphocyte, B-lymphocyte, Epithelial cell, Endothelial cell, Dendritic cell
Targeting
Pancreatic cancer, Colorectal cancer
CXCR4

Source & Reference

TumorHoPe2.0
TumorHoPe2
Methods and reagents for efficient and targeted delivery of therapeutic molecules to CXCR4 cells
2023
US 11590198 B2
US 11590198 B2

Other

Source Activity Label Source Definition
Tumor-homing Peptides
TumorHoPe2.0 experimentally validated tumor-homing peptide annotation.
HeLa cell line
Synthetic(Chemically modified)
Fluorescent protein
At 3rd position L-3-(2-naphtyl)alanine, at 6th position is L-Citrulline, at 8th position is D-Lys and at 12th is L-Citrulline
Additional Detail Fields 2 fields
Fluorescent protein
HeLa cell line