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Peptide record

TPDB93319

Peptide3 Tumor-homing Peptides standard
15 amino acids
Basic Information
3D PDB MODEL
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TPDB93319
Peptide3
Tumor-homing Peptides
Cancer-related peptides
TumorHoPe2.0
standard
No
A 15-aa standard natural tumor-homing peptides peptide sequence curated from TumorHoPe2.0, with an available 3D structural model.
C-terminal: tagged with AuNRs
Sequence
PVRYGFSGPRLAELW
Physicochemical Analysis
C83H122N22O20
NDCQHIKMT
RGLP
1748.02
9.87
2
1
7
+1
-0.45
-0.207
78.00
Mammalian: >20 hour Yeast: >20 hour E.coli: ?
6990
399.88
2
Residue Composition
number
1
A
2
R
0
N
0
D
0
C
1
E
0
Q
2
G
0
H
0
I
2
L
0
K
0
M
1
F
2
P
1
S
0
T
1
W
1
Y
1
V
Amino Acid Distribution
A: 1 R: 2 N: 0 D: 0 C: 0 E: 1 Q: 0 G: 2 H: 0 I: 0 L: 2 K: 0 M: 0 F: 1 P: 2 S: 1 T: 0 W: 1 Y: 1 V: 1
Chemical Descriptors
15
C83H122N22O20
1748.02
9.87
+1
-0.45
-0.207
tagged with AuNRs
Evidence Records 1 records
Evidence 1 Activity

Activity

Tumor-homing Peptides

Target

Tumor cell
Targeting
Breast cancer

Source & Reference

TumorHoPe2.0
TumorHoPe2
Guiding nanomaterials to tumors for breast cancer precision medicine: from tumor-targeting small-molecule discovery to targeted nanodrug delivery
2017
Xuewei Qu et al. NPG Asia Mater. 2017:9:e452.

Other

Source Activity Label Source Definition
Tumor-homing Peptides
TumorHoPe2.0 experimentally validated tumor-homing peptide annotation.
MCF-7 human breast cancer cells
Athymic Nude-Foxn1nu mice (female, 3–5 weeks old)
Phage display library
f3-15mer phage library
Gold nanorods (AuNRs)
Additional Detail Fields 4 fields
Gold nanorods (AuNRs)
MCF-7 human breast cancer cells
Athymic Nude-Foxn1nu mice (female, 3–5 weeks old)
f3-15mer phage library