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Peptide record

TPDB93316

Peptide2 Tumor-homing Peptides standard
15 amino acids
Basic Information
3D PDB MODEL
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TPDB93316
Peptide2
Tumor-homing Peptides
Cancer-related peptides
TumorHoPe2.0
standard
No
A 15-aa standard natural tumor-homing peptides peptide sequence curated from TumorHoPe2.0, with an available 3D structural model.
C-terminal: tagged with AuNRs
Sequence
PKAFQYGGRAVGGLW
Physicochemical Analysis
C76H111N21O18
NDCEHIMST
G
1606.85
10.42
2
0
7
+2
-1.88
-0.193
58.67
Mammalian: >20 hour Yeast: >20 hour E.coli: ?
6990
435.01
2
Residue Composition
number
2
A
1
R
0
N
0
D
0
C
0
E
1
Q
4
G
0
H
0
I
1
L
1
K
0
M
1
F
1
P
0
S
0
T
1
W
1
Y
1
V
Amino Acid Distribution
A: 2 R: 1 N: 0 D: 0 C: 0 E: 0 Q: 1 G: 4 H: 0 I: 0 L: 1 K: 1 M: 0 F: 1 P: 1 S: 0 T: 0 W: 1 Y: 1 V: 1
Chemical Descriptors
15
C76H111N21O18
1606.85
10.42
+2
-1.88
-0.193
tagged with AuNRs
Evidence Records 1 records
Evidence 1 Activity

Activity

Tumor-homing Peptides

Target

Tumor cell
Targeting
Breast cancer

Source & Reference

TumorHoPe2.0
TumorHoPe2
Guiding nanomaterials to tumors for breast cancer precision medicine: from tumor-targeting small-molecule discovery to targeted nanodrug delivery
2017
Xuewei Qu et al. NPG Asia Mater. 2017:9:e452.

Other

Source Activity Label Source Definition
Tumor-homing Peptides
TumorHoPe2.0 experimentally validated tumor-homing peptide annotation.
MCF-7 human breast cancer cells
Athymic Nude-Foxn1nu mice (female, 3–5 weeks old)
Phage display library
f3-15mer phage library
Gold nanorods (AuNRs)
Additional Detail Fields 4 fields
Gold nanorods (AuNRs)
MCF-7 human breast cancer cells
Athymic Nude-Foxn1nu mice (female, 3–5 weeks old)
f3-15mer phage library