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Peptide record

TPDB93311

CKAAKN Tumor-homing Peptides standard
6 amino acids
Basic Information
3D PDB MODEL
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TPDB93311
CKAAKN
Tumor-homing Peptides
Cancer-related peptides
TumorHoPe2.0
standard
No
A 6-aa standard natural tumor-homing peptides peptide sequence curated from TumorHoPe2.0, with an available 3D structural model.
N-terminal: 6-carbon atom lipophilic chain with a maleimide terminal group
Sequence
CKAAKN
Physicochemical Analysis
C25H47N9O8S1
RDEQGHILMFPSTWYV
AK
633.76
9.90
2
0
2
+2
1.82
-0.867
33.33
Mammalian: 1.2 hour Yeast: >20 hour E.coli: >10 hour
0
0.00
2
Residue Composition
number
2
A
0
R
1
N
0
D
1
C
0
E
0
Q
0
G
0
H
0
I
0
L
2
K
0
M
0
F
0
P
0
S
0
T
0
W
0
Y
0
V
Amino Acid Distribution
A: 2 R: 0 N: 1 D: 0 C: 1 E: 0 Q: 0 G: 0 H: 0 I: 0 L: 0 K: 2 M: 0 F: 0 P: 0 S: 0 T: 0 W: 0 Y: 0 V: 0
Chemical Descriptors
6
C25H47N9O8S1
633.76
9.90
+2
1.82
-0.867
6-carbon atom lipophilic chain with a maleimide terminal group
Evidence Records 1 records
Evidence 1 Activity

Activity

Tumor-homing Peptides

Target

Tumor cell, angiogenic vessel
Targeting
Pancreatic cancer
Frizzled (FZD-5) receptors

Source & Reference

TumorHoPe2.0
TumorHoPe2
Peptide-functionalized nanoparticles for selective targeting of pancreatic tumor
2014
Valetti S et al. J Control Release. 2014 Oct 28:192:29-39.

Other

Source Activity Label Source Definition
Tumor-homing Peptides
TumorHoPe2.0 experimentally validated tumor-homing peptide annotation.
Tumor-bearing RIP-Tag2 mice
Synthetic
Squalene, Gemcitabine
Additional Detail Fields 2 fields
Squalene, Gemcitabine
Tumor-bearing RIP-Tag2 mice