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Peptide record

TPDB93286

peptide 12 Cell-penetrating Peptides standard
16 amino acids
Basic Information
3D PDB MODEL
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TPDB93286
peptide 12
Cell-penetrating Peptides
Delivery and barrier-penetrating peptides
CellPPD CellPPD-MOD CPPsite3.0 MLCPP 2.0 Peptipedia PerseuCPP
standard
No
A 16-aa standard natural cell-penetrating peptides peptide sequence curated from CellPPD, CellPPD-MOD, CPPsite3.0, and other sources, with an available 3D structural model.
N-terminal: Conjugated with 6-Carboxyfluorescein (6-Fam)
Sequence
YTAIAWVKAFIRKLRK
Physicochemical Analysis
C95H154N26O19
NDCEQGHMPS
AK
1964.43
11.59
5
0
10
+5
-0.81
0.100
110.00
Mammalian: 2.8 hour Yeast: 10 min E.coli: 2 min
6990
355.83
2
Residue Composition
number
3
A
2
R
0
N
0
D
0
C
0
E
0
Q
0
G
0
H
2
I
1
L
3
K
0
M
1
F
0
P
0
S
1
T
1
W
1
Y
1
V
Amino Acid Distribution
A: 3 R: 2 N: 0 D: 0 C: 0 E: 0 Q: 0 G: 0 H: 0 I: 2 L: 1 K: 3 M: 0 F: 1 P: 0 S: 0 T: 1 W: 1 Y: 1 V: 1
Chemical Descriptors
16
C95H154N26O19
1964.43
11.59
+5
-0.81
0.100
Free
L
Amphipathic
Linear
Conjugated with 6-Carboxyfluorescein (6-Fam)
N[C@@H](CS)C(=O)N[C@@H](CC1=CN=C(C)/C/1=C\C)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCCN)C(=O)O
Evidence Records 1 records
Evidence 1 Activity

Activity

Cell-penetrating Peptides

Target

HeLa Cells

Source & Reference

CPPsite3.0
CPPsite3

Other

Source Activity Label Source Definition
Cell-penetrating Peptides
CPPsite3.0 experimentally validated cell-penetrating peptide annotation.
Natural residues Linear L Amphipathic
5(6)-carboxyfluorescein (FAM) dye
401.31 RFU
In vitro
CCCCCCGGGGGCCSCCCTTC
Additional Detail Fields 1 fields
CCCCCCGGGGGCCSCCCTTC