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Peptide record

TPDB93279

NrTP6 Cell-penetrating Peptides standard
14 amino acids
Basic Information
3D PDB MODEL
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TPDB93279
NrTP6
Cell-penetrating Peptides
Delivery and barrier-penetrating peptides
CPPsite3.0 MLCPP 2.0 Peptipedia PerseuCPP
standard
No
A 14-aa standard natural cell-penetrating peptides peptide sequence curated from CPPsite3.0, MLCPP 2.0, Peptipedia, and other sources, with an available 3D structural model.
N-terminal: Conjugation with rhodamine B
Sequence
YKQSHKKGGKKGSG
Physicochemical Analysis
C64H108N22O19
ARNDCEILMFPTWV
K
1489.70
10.77
6
0
1
+5
5.85
-2.193
0.00
Mammalian: 2.8 hour Yeast: 10 min E.coli: 2 min
1490
100.02
4
Residue Composition
number
0
A
0
R
0
N
0
D
0
C
0
E
1
Q
4
G
1
H
0
I
0
L
5
K
0
M
0
F
0
P
2
S
0
T
0
W
1
Y
0
V
Amino Acid Distribution
A: 0 R: 0 N: 0 D: 0 C: 0 E: 0 Q: 1 G: 4 H: 1 I: 0 L: 0 K: 5 M: 0 F: 0 P: 0 S: 2 T: 0 W: 0 Y: 1 V: 0
Chemical Descriptors
14
C64H108N22O19
1489.70
10.77
+5
5.85
-2.193
Free
L
Linear
Conjugation with rhodamine B
N[C@@H](Cc1ccccc1)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCC(=O)N)C(=O)N[C@@H](CO)C(=O)N[C@@H](CC1=NC=NC1)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCCN)C(=O)NCC(=O)NCC(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCCN)C(=O)NCC(=O)N[C@@H](CO)C(=O)NCC(=O)O
Evidence Records 2 records
Evidence 1 Activity

Activity

Cell-penetrating Peptides

Target

PBMCs

Source & Reference

CPPsite3.0
CPPsite3

Other

Source Activity Label Source Definition
Cell-penetrating Peptides
CPPsite3.0 experimentally validated cell-penetrating peptide annotation.
Natural residues Linear L
Synthetic
Fluorophore (Rhodamine B)
Endocytic pathway
In vitro
CCCSSCCTTSCCC
Evidence 2 Activity

Activity

Cell-penetrating Peptides

Target

Hela, Molt-4 and erythrocytes

Source & Reference

CPPsite3.0
CPPsite3

Other

Natural residues Linear L
Protein derived
Fluorophore (Rhodamine B )
Cytoplasm
In vitro
CCCSSCCTTSCCC
Additional Detail Fields 1 fields
CCCSSCCTTSCCC