Back to search

Peptide record

TPDB93271

CAMP Cell-penetrating Peptides standard
22 amino acids
Basic Information
3D PDB MODEL
Drag to rotate. Click a residue or atom to inspect it; the selected residue is highlighted in amber.
TPDB93271
CAMP
Cell-penetrating Peptides
Delivery and barrier-penetrating peptides
CPPsite3.0
standard
No
A 22-aa standard natural cell-penetrating peptides peptide sequence curated from CPPsite3.0, with an available 3D structural model.
Chemical: 6xHis
Sequence
YGRKKRRQRRRLLRAALRKAAL
Physicochemical Analysis
C118H218N50O25
NDCEHIMFPSTWV
R
2737.35
12.88
11
0
9
+11
6.18
-1.386
89.09
Mammalian: 2.8 hour Yeast: 10 min E.coli: 2 min
1490
54.43
2
Residue Composition
number
4
A
8
R
0
N
0
D
0
C
0
E
1
Q
1
G
0
H
0
I
4
L
3
K
0
M
0
F
0
P
0
S
0
T
0
W
1
Y
0
V
Amino Acid Distribution
A: 4 R: 8 N: 0 D: 0 C: 0 E: 0 Q: 1 G: 1 H: 0 I: 0 L: 4 K: 3 M: 0 F: 0 P: 0 S: 0 T: 0 W: 0 Y: 1 V: 0
Chemical Descriptors
22
C118H218N50O25
2737.35
12.88
+11
6.18
-1.386
Free
6xHis
L
Linear
Free
N[C@@H](Cc1ccccc1)C(=O)N[C@@H](CCCN=C)C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H](CCCCN)C(=O)O
Evidence Records 1 records
Evidence 1 Activity

Activity

Cell-penetrating Peptides

Target

Sk-Hep1, SH-SY5Y

Assay & Model

Male C57BL6 mice (8 weeks old, 19–22 g)
Male C57BL6 mice (8 weeks old, 19–22 g)

Source & Reference

CPPsite3.0
CPPsite3

Other

Source Activity Label Source Definition
Cell-penetrating Peptides
CPPsite3.0 experimentally validated cell-penetrating peptide annotation.
Natural residues Linear L
Synthetic
Human metallothionein 1A (hMT1A)
Mitochondria
CAMP-hMT1A was found in Mitochondria as early as 3 h after incubation
In vitro and in vivo
CCCC
Additional Detail Fields 1 fields
CCCC