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Peptide record

TPDB93269

biotinyl-TAT Cell-penetrating Peptides standard
12 amino acids
Basic Information
3D PDB MODEL
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TPDB93269
biotinyl-TAT
Cell-penetrating Peptides
Delivery and barrier-penetrating peptides
CPPsite3.0
standard
No
A 12-aa standard natural cell-penetrating peptides peptide sequence curated from CPPsite3.0, with an available 3D structural model.
C-terminal: Amidation Chemical: Fmoc-Lys(biotin)−OH was linked with the C-terminus N-terminal: Biotinylation
Sequence
YGRKKRRQRRRK-NH2
Physicochemical Analysis
C70H130N34O15
ANDCEHILMFPSTWV
R
1688.02
12.71
9
0
1
+9
7.48
-3.658
0.00
Mammalian: 2.8 hour Yeast: 10 min E.coli: 2 min
1490
88.27
2
Residue Composition
number
0
A
6
R
0
N
0
D
0
C
0
E
1
Q
1
G
0
H
0
I
0
L
3
K
0
M
0
F
0
P
0
S
0
T
0
W
1
Y
0
V
Amino Acid Distribution
A: 0 R: 6 N: 0 D: 0 C: 0 E: 0 Q: 1 G: 1 H: 0 I: 0 L: 0 K: 3 M: 0 F: 0 P: 0 S: 0 T: 0 W: 0 Y: 1 V: 0
Chemical Descriptors
12
C70H130N34O15
1688.02
12.71
+9
7.48
-3.658
Amidation
Fmoc-Lys(biotin)−OH was linked with the C-terminus
L
Linear
Biotinylation
N[C@@H](Cc1ccccc1)C(=O)NCC(=O)N[C@@H](CCCN=C)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCN=C)C(=O)N[C@@H](CCCN=C)C(=O)N[C@@H](CCC(=O)N)C(=O)N[C@@H](CCCN=C)C(=O)N[C@@H](CCCN=C)C(=O)N[C@@H](CCCN=C)C(=O)N[C@@H](CCCCN)C(=O)O
Evidence Records 1 records
Evidence 1 Activity

Activity

Cell-penetrating Peptides

Target

B16, Cos7, And HeLa Cells

Source & Reference

CPPsite3.0
CPPsite3

Other

Source Activity Label Source Definition
Cell-penetrating Peptides
CPPsite3.0 experimentally validated cell-penetrating peptide annotation.
Natural residues Linear L
Protein derived
FITC-labeled Avidin
Lysosomes
Macropinocytosis
In vitro
CCSCTTSCCCCC
Additional Detail Fields 1 fields
CCSCTTSCCCCC