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Peptide record

TPDB93229

NF-kB Cell-penetrating Peptides standard
10 amino acids
Basic Information
3D PDB MODEL
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TPDB93229
NF-kB
Cell-penetrating Peptides
Delivery and barrier-penetrating peptides
CellPPD CellPPD-MOD CPPsite3.0 Peptipedia
standard
No
A 10-aa standard natural cell-penetrating peptides peptide sequence curated from CellPPD, CellPPD-MOD, CPPsite3.0, and other sources, with an available 3D structural model.
C-terminal: Amidation N-terminal: Conjugation with fluorescein
Sequence
VQRKRQKLMP-NH2
Physicochemical Analysis
C55H102N20O13S1
ANDCEGHIFSTWY
RQK
1283.60
12.42
4
0
3
+4
4.49
-1.550
68.00
Mammalian: 100 hour Yeast: >20 hour E.coli: >10 hour
0
0.00
2
Residue Composition
number
0
A
2
R
0
N
0
D
0
C
0
E
2
Q
0
G
0
H
0
I
1
L
2
K
1
M
0
F
1
P
0
S
0
T
0
W
0
Y
1
V
Amino Acid Distribution
A: 0 R: 2 N: 0 D: 0 C: 0 E: 0 Q: 2 G: 0 H: 0 I: 0 L: 1 K: 2 M: 1 F: 0 P: 1 S: 0 T: 0 W: 0 Y: 0 V: 1
Chemical Descriptors
10
C55H102N20O13S1
1283.60
12.42
+4
4.49
-1.550
Amidation
L
Cationic
Linear
Conjugation with fluorescein
N[C@@H](C(C)C)C(=O)N[C@@H](CCC(=O)N)C(=O)N[C@@H](CCCN=C)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCN=C)C(=O)N[C@@H](CCC(=O)N)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CCSC)C(=O)N1CCC[C@H]1C(=O)O
Evidence Records 1 records
Evidence 1 Activity

Activity

Cell-penetrating Peptides

Target

MCF-7

Source & Reference

CPPsite3.0
CPPsite3

Other

Source Activity Label Source Definition
Cell-penetrating Peptides
CPPsite3.0 experimentally validated cell-penetrating peptide annotation.
Natural residues Linear L Cationic
Protein derived
Fluorophore (fluorescein)
Cytoplasm and nucleus, nucleolus
Lower than Oct-6
Energy dependent endocytic pathway
In vitro
CCBTTBSSCC
Additional Detail Fields 1 fields
CCBTTBSSCC