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Peptide record

TPDB93217

Sweet Arrow Protein (SAP) (E) Blood-Brain Barrier Cell-penetrating Peptides standard
18 amino acids
Basic Information
3D PDB MODEL
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TPDB93217
Sweet Arrow Protein (SAP) (E)
Blood-Brain Barrier Cell-penetrating Peptides
Delivery and barrier-penetrating peptides
BBPpredict CellPPD CPPsite3.0 MLCPP 2.0 Peptipedia PerseuCPP
standard
No
A 18-aa standard natural multi-activity (Blood-Brain Barrier and Cell-penetrating Peptides) peptide sequence curated from BBPpredict, CellPPD, CPPsite3.0, and other sources, with an available 3D structural model.
N-terminal: Conjugation with fluorescein/ rhodamine B
Sequence
VELPPPVELPPPVELPPP
Physicochemical Analysis
C93H146N18O25
ARNDCQGHIKMFSTWY
P
1916.29
3.03
0
3
6
-3
8.64
-0.050
113.33
Mammalian: 100 hour Yeast: >20 hour E.coli: >10 hour
0
0.00
0
Residue Composition
number
0
A
0
R
0
N
0
D
0
C
3
E
0
Q
0
G
0
H
0
I
3
L
0
K
0
M
0
F
9
P
0
S
0
T
0
W
0
Y
3
V
Amino Acid Distribution
A: 0 R: 0 N: 0 D: 0 C: 0 E: 3 Q: 0 G: 0 H: 0 I: 0 L: 3 K: 0 M: 0 F: 0 P: 9 S: 0 T: 0 W: 0 Y: 0 V: 3
Chemical Descriptors
18
C93H146N18O25
1916.29
3.03
-3
8.64
-0.050
Free
L
Amphipathic
Linear
Conjugation with fluorescein/ rhodamine B
N[C@@H](C(C)C)C(=O)N[C@@H](CCC(=O)O)C(=O)N[C@@H](CC(C)C)C(=O)N1CCC[C@H]1C(=O)N1CCC[C@H]1C(=O)N1CCC[C@H]1C(=O)N[C@@H](C(C)C)C(=O)N[C@@H](CCC(=O)O)C(=O)N[C@@H](CC(C)C)C(=O)N1CCC[C@H]1C(=O)N1CCC[C@H]1C(=O)N1CCC[C@H]1C(=O)N[C@@H](C(C)C)C(=O)N[C@@H](CCC(=O)O)C(=O)N[C@@H](CC(C)C)C(=O)N1CCC[C@H]1C(=O)N1CCC[C@H]1C(=O)N1CCC[C@H]1C(=O)O
Evidence Records 1 records
Evidence 1 Activity

Activity

Cell-penetrating Peptides

Target

HeLa, A549, BJ and HT cells

Source & Reference

CPPsite3.0
CPPsite3

Other

Source Activity Label Source Definition
Cell-penetrating Peptides
CPPsite3.0 experimentally validated cell-penetrating peptide annotation.
Natural residues Linear L Amphipathic
Protein derived
Fluorophore (fluoresceine/ rhodamine)
Punctuated distribution (vesicles)
Comparable to L-SAP
Caveolae-mediated and lipid raft-mediated endocytosis
In vitro
CCCCTTCCCCCCCCCCCC
Additional Detail Fields 1 fields
CCCCTTCCCCCCCCCCCC