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Peptide record

TPDB93212

Inv11 Inv3 Cell-penetrating Peptides standard
22 amino acids
Basic Information
3D PDB MODEL
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TPDB93212
Inv11 Inv3
Cell-penetrating Peptides
Delivery and barrier-penetrating peptides
CellPPD CPPsite3.0 Peptipedia PerseuCPP
standard
No
A 22-aa standard natural cell-penetrating peptides peptide sequence curated from CellPPD, CPPsite3.0, Peptipedia, and other sources, with an available 3D structural model.
N-terminal: Free (peptide coated FITC labelled microspheres)
Sequence
TKRRITPKDVIDVRSVTTEINT
Physicochemical Analysis
C108H192N34O36
ACQGHLMFWY
T
2542.92
10.56
5
3
6
+2
9.87
-0.686
92.73
Mammalian: 7.2 hour Yeast: >20 hour E.coli: >10 hour
0
0.00
7
Residue Composition
number
0
A
3
R
1
N
2
D
0
C
1
E
0
Q
0
G
0
H
3
I
0
L
2
K
0
M
0
F
1
P
1
S
5
T
0
W
0
Y
3
V
Amino Acid Distribution
A: 0 R: 3 N: 1 D: 2 C: 0 E: 1 Q: 0 G: 0 H: 0 I: 3 L: 0 K: 2 M: 0 F: 0 P: 1 S: 1 T: 5 W: 0 Y: 0 V: 3
Chemical Descriptors
22
C108H192N34O36
2542.92
10.56
+2
9.87
-0.686
Free
L
Linear
Free (peptide coated FITC labelled microspheres)
N[C@@H]([C@@H](C)O)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCN=C)C(=O)N[C@@H](CCCN=C)C(=O)N[C@@H]([C@@H](C)CC)C(=O)N[C@@H]([C@@H](C)O)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CC(=O)O)C(=O)N[C@@H](C(C)C)C(=O)N[C@@H]([C@@H](C)CC)C(=O)N[C@@H](CC(=O)O)C(=O)N[C@@H](C(C)C)C(=O)N[C@@H](CCCN=C)C(=O)N[C@@H](CO)C(=O)N[C@@H](C(C)C)C(=O)N[C@@H]([C@@H](C)O)C(=O)N[C@@H]([C@@H](C)O)C(=O)N[C@@H](CCC(=O)O)C(=O)N[C@@H]([C@@H](C)CC)C(=O)N[C@@H](CC(=O)N)C(=O)N[C@@H]([C@@H](C)O)C(=O)O
Evidence Records 2 records
Evidence 1 Activity

Activity

Cell-penetrating Peptides

Target

HeLa

Source & Reference

CPPsite3.0
CPPsite3

Other

Source Activity Label Source Definition
Cell-penetrating Peptides
CPPsite3.0 experimentally validated cell-penetrating peptide annotation.
Natural residues Linear L
Protein derived
Nanoparticle [(FITC)-labeled latex microspheres]
Cytoplasm and nucleus membrane
High
Endocytic pathway
In vitro
CCSCSSSCCSCCTTTTTSCCCC
Evidence 2 Activity

Activity

Cell-penetrating Peptides

Target

HeLa

Source & Reference

CPPsite3.0
CPPsite3

Other

Natural residues Linear L
Protein derived
Nanoparticle [(FITC)-labeled latex microspheres]
Cytoplasm and nucleus membrane
Low (relative to Inv3)
In vitro
CCSCSSSCCSCCTTTTTSCCCC
Additional Detail Fields 1 fields
CCSCSSSCCSCCTTTTTSCCCC