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Peptide record

TPDB93204

HPV33L2-445/467 Cell-penetrating Peptides standard
23 amino acids
Basic Information
3D PDB MODEL
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TPDB93204
HPV33L2-445/467
Cell-penetrating Peptides
Delivery and barrier-penetrating peptides
CPPsite3.0
standard
No
A 23-aa standard natural cell-penetrating peptides peptide sequence curated from CPPsite3.0, with an available 3D structural model.
C-terminal: Conjugated with TAMRA Chemical: Lys side chain amine at the C-terminus
Sequence
SYFILRRRRKRFPYFFTDVRVAA
Physicochemical Analysis
C140H214N42O30
NCEQGHMW
R
2965.50
12.11
7
1
12
+6
0.33
-0.374
67.83
Mammalian: 1.9 hour Yeast: >20 hour E.coli: >10 hour
2980
100.49
4
Residue Composition
number
2
A
6
R
0
N
1
D
0
C
0
E
0
Q
0
G
0
H
1
I
1
L
1
K
0
M
4
F
1
P
1
S
1
T
0
W
2
Y
2
V
Amino Acid Distribution
A: 2 R: 6 N: 0 D: 1 C: 0 E: 0 Q: 0 G: 0 H: 0 I: 1 L: 1 K: 1 M: 0 F: 4 P: 1 S: 1 T: 1 W: 0 Y: 2 V: 2
Chemical Descriptors
23
C140H214N42O30
2965.50
12.11
+6
0.33
-0.374
Conjugated with TAMRA
Lys side chain amine at the C-terminus
L
Amphipathic
Linear
Free
N[C@@H](CO)C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H]([C@@H](C)CC)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CCCN=C)C(=O)N[C@@H](CCCN=C)C(=O)N[C@@H](CCCN=C)C(=O)N[C@@H](CCCN=C)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCN=C)C(=O)N[C@@H](Cc1ccccc1)C(=O)N1CCC[C@H]1C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H]([C@@H](C)O)C(=O)N[C@@H](CC(=O)O)C(=O)N[C@@H](C(C)C)C(=O)N[C@@H](CCCN=C)C(=O)N[C@@H](C(C)C)C(=O)N[C@@H](C)C(=O)N[C@@H](C)C(=O)O
Evidence Records 1 records
Evidence 1 Activity

Activity

Cell-penetrating Peptides

Target

By-2 Cells Leaves Of Nicotiana Benthamiana, Arabidopsis Thaliana, Tomato (Solanum Lycopersicum), Poplar (Hybrid Aspen Populus Tremula×Tremuloides Line T89), And Rice (Oryza Sativa).

Source & Reference

CPPsite3.0
CPPsite3

Other

Source Activity Label Source Definition
Cell-penetrating Peptides
CPPsite3.0 experimentally validated cell-penetrating peptide annotation.
Natural residues Linear L Amphipathic
TAMRA dye
HPV33L2-445/467 have medium efficiency in BY-2 cells.
In vitro
CCCCCCCSSCCCSSSTTTSCCCC
Additional Detail Fields 1 fields
CCCCCCCSSCCCSSSTTTSCCCC