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Peptide record

TPDB93199

SDSSD Cell-penetrating Peptides modified_plain modified
5 amino acids
Basic Information
3D PDB MODEL
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Sequence-matched coordinates; source-recorded chemical modifications are not verified in this model.

TPDB93199
SDSSD
Cell-penetrating Peptides
Delivery and barrier-penetrating peptides
CPPsite3.0
modified_plain
Yes
A 5-aa modified cell-penetrating peptides peptide sequence curated from CPPsite3.0, with an available 3D structural model.
Chemical: DTBTA-Eu3+ -labelled
Sequence
SDSSD
Physicochemical Analysis

Sequence-only estimates are not provided for modified or non-standard source notation. Reported molecular properties, when available, are retained below with their source records.

Chemical Descriptors
5 main sequence record
Free Activity
DTBTA-Eu3+ -labelled Activity
L Activity
Linear Activity
Free Activity
N[C@@H](CCSC)C(=O)N[C@@H]([C@@H](C)O)C(=O)N1CCC[C@H]1C(=O)N[C@@H]([C@@H](C)O)C(=O)N[C@@H](C)C(=O)N[C@@H](CC(=O)N)C(=O)N[C@@H]([C@@H](C)O)C(=O)N[C@@H](CS)C(=O)N[C@@H](C(C)C)C(=O)N[C@@H](CCCN=C)C(=O)N[C@@H](CS)C(=O)N[C@@H](CC(=O)N)C(=O)O Activity
Evidence Records 1 records
Evidence 1 Activity

Activity

Cell-penetrating Peptides

Assay & Model

C57BL/6 mice (female, 8–10 weeks of age) were infected subcutaneously with S. aureus Cowan I
C57BL/6 mice (female, 8–10 weeks of age) were infected subcutaneously with S. aureus Cowan I

Source & Reference

CPPsite3.0
CPPsite3

Other

Source Activity Label Source Definition
Cell-penetrating Peptides
CPPsite3.0 experimentally validated cell-penetrating peptide annotation.
Natural residues Linear L
Phage Display
LST fused at C terminal
Significantly higher levels of LST_HGDWT (P = 0.033) and LST_SDSSD (P = 0.009) as compared to the parental LST were observed in bone
In vivo
CCCCCCCCCCCC
Additional Detail Fields 1 fields
CCCCCCCCCCCC