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Peptide record

TPDB93179

R7W Cell-penetrating Peptides standard
8 amino acids
Basic Information
3D PDB MODEL
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TPDB93179
R7W
Cell-penetrating Peptides
Delivery and barrier-penetrating peptides
CellPPD CellPPD-MOD CPPsite3.0 MLCPP 2.0 Peptipedia PerseuCPP
standard
No
A 8-aa standard natural cell-penetrating peptides peptide sequence curated from CellPPD, CellPPD-MOD, CPPsite3.0, and other sources, with an available 3D structural model.
C-terminal: Amidation N-terminal: Conjugation with fluorescein
Sequence
RRRRRRRW-NH2
Physicochemical Analysis
C53H96N30O9
ANDCEQGHILKMFPSTYV
R
1297.54
13.18
7
0
1
+7
3.82
-4.050
0.00
Mammalian: 1 hour Yeast: 2 min E.coli: 2 min
5500
423.88
0
Residue Composition
number
0
A
7
R
0
N
0
D
0
C
0
E
0
Q
0
G
0
H
0
I
0
L
0
K
0
M
0
F
0
P
0
S
0
T
1
W
0
Y
0
V
Amino Acid Distribution
A: 0 R: 7 N: 0 D: 0 C: 0 E: 0 Q: 0 G: 0 H: 0 I: 0 L: 0 K: 0 M: 0 F: 0 P: 0 S: 0 T: 0 W: 1 Y: 0 V: 0
Chemical Descriptors
8
C53H96N30O9
1297.54
13.18
+7
3.82
-4.050
Amidation
L
Cationic
Linear
Conjugation with fluorescein
N[C@@H](CCCN=C)C(=O)N[C@@H](CCCN=C)C(=O)N[C@@H](CCCN=C)C(=O)N[C@@H](CCCN=C)C(=O)N[C@@H](CCCN=C)C(=O)N[C@@H](CCCN=C)C(=O)N[C@@H](CCCN=C)C(=O)N[C@@H](CC1=C(C(=NC1)C)CC)C(=O)O
Evidence Records 1 records
Evidence 1 Activity

Activity

Cell-penetrating Peptides

Target

PC-12 and V79 cells

Source & Reference

CPPsite3.0
CPPsite3

Other

Source Activity Label Source Definition
Cell-penetrating Peptides
CPPsite3.0 experimentally validated cell-penetrating peptide annotation.
Natural residues Linear L Cationic
Synthetic
Fluorophore (fluorescein)
Cytoplasm and nucleus
Energy-independent non-endocytic pathway
In vitro
CCCCCCCC
Additional Detail Fields 1 fields
CCCCCCCC