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Peptide record

TPDB93159

PN81 (SEQ ID NO: 41) Cell-penetrating Peptides standard
29 amino acids
Basic Information
3D PDB MODEL
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TPDB93159
PN81 (SEQ ID NO: 41)
Cell-penetrating Peptides
Delivery and barrier-penetrating peptides
CellPPD CellPPD-MOD CPPsite3.0 MLCPP 2.0 Peptipedia PerseuCPP
standard
No
A 29-aa standard natural cell-penetrating peptides peptide sequence curated from CellPPD, CellPPD-MOD, CPPsite3.0, and other sources, with an available 3D structural model.
C-terminal: Amidation N-terminal: Bromoacetylation
Sequence
RRRQRRKRGGDIMGEWGNEIFGAIAGFLG-NH2
Physicochemical Analysis
C143H231N51O38S1
CHPSTYV
G
3304.79
12.11
7
3
10
+4
6.02
-0.817
60.69
Mammalian: 1 hour Yeast: 2 min E.coli: 2 min
5500
166.43
2
Residue Composition
number
2
A
6
R
1
N
1
D
0
C
2
E
1
Q
7
G
0
H
3
I
1
L
1
K
1
M
2
F
0
P
0
S
0
T
1
W
0
Y
0
V
Amino Acid Distribution
A: 2 R: 6 N: 1 D: 1 C: 0 E: 2 Q: 1 G: 7 H: 0 I: 3 L: 1 K: 1 M: 1 F: 2 P: 0 S: 0 T: 0 W: 1 Y: 0 V: 0
Chemical Descriptors
29
C143H231N51O38S1
3304.79
12.11
+4
6.02
-0.817
Amidation
L
Linear
Bromoacetylation
N[C@@H](CCCN=C)C(=O)N[C@@H](CCCN=C)C(=O)N[C@@H](CCCN=C)C(=O)N[C@@H](CCC(=O)N)C(=O)N[C@@H](CCCN=C)C(=O)N[C@@H](CCCN=C)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCN=C)C(=O)NCC(=O)NCC(=O)N[C@@H](CC(=O)O)C(=O)N[C@@H]([C@@H](C)CC)C(=O)N[C@@H](CCSC)C(=O)NCC(=O)N[C@@H](CCC(=O)O)C(=O)N[C@@H](CC1=CN=C(C)/C/1=C\C)C(=O)NCC(=O)N[C@@H](CC(=O)N)C(=O)N[C@@H](CCC(=O)O)C(=O)N[C@@H]([C@@H](C)CC)C(=O)N[C@@H](Cc1ccccc1)C(=O)NCC(=O)N[C@@H](C)C(=O)N[C@@H]([C@@H](C)CC)C(=O)N[C@@H](C)C(=O)NCC(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H](CC(C)C)C(=O)NCC(=O)O
Evidence Records 1 records
Evidence 1 Activity

Activity

Cell-penetrating Peptides

Target

9 L/LacZ cells

Source & Reference

CPPsite3.0
CPPsite3
US 20060035815

Other

Source Activity Label Source Definition
Cell-penetrating Peptides
CPPsite3.0 experimentally validated cell-penetrating peptide annotation.
Natural residues Linear L
Synthetic
Nucleic acid (siRNA)
In vitro
CCSTTSSCCCSSSTTTSCSSSTTCCTTCC
Additional Detail Fields 1 fields
CCSTTSSCCCSSSTTTSCSSSTTCCTTCC