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Peptide record

TPDB93153

Biotin-P7 Cell-penetrating Peptides standard
7 amino acids
Basic Information
3D PDB MODEL
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TPDB93153
Biotin-P7
Cell-penetrating Peptides
Delivery and barrier-penetrating peptides
CellPPD CellPPD-MOD CPPsite3.0 Peptipedia PerseuCPP
standard
No
A 7-aa standard natural cell-penetrating peptides peptide sequence curated from CellPPD, CellPPD-MOD, CPPsite3.0, and other sources, with an available 3D structural model.
C-terminal: Amidation N-terminal: Biotinylation via Β-Glycine
Sequence
RRMKWKK-NH2
Physicochemical Analysis
C46H81N17O8S1
ANDCEQGHILFPSTYV
K
1032.32
12.43
5
0
2
+5
2.51
-2.814
0.00
Mammalian: 1 hour Yeast: 2 min E.coli: 2 min
5500
532.78
0
Residue Composition
number
0
A
2
R
0
N
0
D
0
C
0
E
0
Q
0
G
0
H
0
I
0
L
3
K
1
M
0
F
0
P
0
S
0
T
1
W
0
Y
0
V
Amino Acid Distribution
A: 0 R: 2 N: 0 D: 0 C: 0 E: 0 Q: 0 G: 0 H: 0 I: 0 L: 0 K: 3 M: 1 F: 0 P: 0 S: 0 T: 0 W: 1 Y: 0 V: 0
Chemical Descriptors
7
C46H81N17O8S1
1032.32
12.43
+5
2.51
-2.814
Amidation
L
Linear
Biotinylation via Β-Glycine
N[C@@H](Cc1ccccc1)C(=O)NCC(=O)N[C@@H](CCCN=C)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCN=C)C(=O)N[C@@H](CCCN=C)C(=O)N[C@@H](CCC(=O)N)C(=O)N[C@@H](CCCN=C)C(=O)N[C@@H](CCCN=C)C(=O)N[C@@H](CCCN=C)C(=O)N[C@@H](CCCCN)C(=O)O
Evidence Records 1 records
Evidence 1 Activity

Activity

Cell-penetrating Peptides

Target

HeLa Cells

Source & Reference

CPPsite3.0
CPPsite3

Other

Source Activity Label Source Definition
Cell-penetrating Peptides
CPPsite3.0 experimentally validated cell-penetrating peptide annotation.
Natural residues Linear L
Synthetic
Biotin
No significant difference in the level of intracellular biotin with either Biotin-P16 or Biotin-P7.
In vitro
CCSCTTSCCCCC
Additional Detail Fields 1 fields
CCSCTTSCCCCC