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Peptide record

TPDB93150

SynB3 Blood-Brain Barrier Cell-penetrating Peptides standard
10 amino acids
Basic Information
3D PDB MODEL
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TPDB93150
SynB3
Blood-Brain Barrier Cell-penetrating Peptides
Delivery and barrier-penetrating peptides
B3Pred BBPpredict Peptipedia CellPPD CellPPD-MOD CPPsite3.0 MLCPP 2.0
standard
No
A 10-aa standard natural multi-activity (Blood-Brain Barrier and Cell-penetrating Peptides) peptide sequence curated from B3Pred, BBPpredict, Peptipedia, and other sources, with an available 3D structural model.
N-terminal: Conjugation with NBD and TAMRA
Sequence
RRLSYSRRRF
Physicochemical Analysis
C60H101N25O14
ANDCEQGHIKMPTWV
R
1396.62
12.58
5
0
3
+5
1.68
-1.880
39.00
Mammalian: 1 hour Yeast: 2 min E.coli: 2 min
1490
106.69
3
Residue Composition
number
0
A
5
R
0
N
0
D
0
C
0
E
0
Q
0
G
0
H
0
I
1
L
0
K
0
M
1
F
0
P
2
S
0
T
0
W
1
Y
0
V
Amino Acid Distribution
A: 0 R: 5 N: 0 D: 0 C: 0 E: 0 Q: 0 G: 0 H: 0 I: 0 L: 1 K: 0 M: 0 F: 1 P: 0 S: 2 T: 0 W: 0 Y: 1 V: 0
Chemical Descriptors
10
C60H101N25O14
1396.62
12.58
+5
1.68
-1.880
Free
L
Antimicrobial
Linear
Conjugation with NBD and TAMRA
N[C@@H](CCCN=C)C(=O)N[C@@H](CCCN=C)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CO)C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H](CO)C(=O)N[C@@H](CCCN=C)C(=O)N[C@@H](CCCN=C)C(=O)N[C@@H](CCCN=C)C(=O)N[C@@H](Cc1ccccc1)C(=O)O
Evidence Records 1 records
Evidence 1 Activity

Activity

Cell-penetrating Peptides

Target

K562 cells

Source & Reference

CPPsite3.0
CPPsite3

Other

Source Activity Label Source Definition
Cell-penetrating Peptides
CPPsite3.0 experimentally validated cell-penetrating peptide annotation.
Natural residues Linear L Antimicrobial
Protein derived
Fluorophore (NBD and TAMRA)
Endocytic vesicles
Lower than pAntp-(43–58) and SynB5
Adsorptive-mediated endocytic process
In vitro
CCCCCCTTCC
Additional Detail Fields 1 fields
CCCCCCTTCC