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Peptide record

TPDB93131

pAntpHD(Pro50) Cell-penetrating Peptides standard
16 amino acids
Basic Information
3D PDB MODEL
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TPDB93131
pAntpHD(Pro50)
Cell-penetrating Peptides
Delivery and barrier-penetrating peptides
CellPPD CellPPD-MOD CPPsite3.0 Peptipedia PerseuCPP
standard
No
A 16-aa standard natural cell-penetrating peptides peptide sequence curated from CellPPD, CellPPD-MOD, CPPsite3.0, and other sources, with an available 3D structural model.
C-terminal: Conjugated with TAMRA Chemical: Lys side chain amine at the C-terminus
Sequence
RQIKIWFPNRRMKWKK
Physicochemical Analysis
C104H167N33O19S1
ADCEGHLSTYV
K
2215.74
12.72
7
0
6
+7
2.16
-1.612
48.75
Mammalian: 1 hour Yeast: 2 min E.coli: 2 min
11000
496.45
2
Residue Composition
number
0
A
3
R
1
N
0
D
0
C
0
E
1
Q
0
G
0
H
2
I
0
L
4
K
1
M
1
F
1
P
0
S
0
T
2
W
0
Y
0
V
Amino Acid Distribution
A: 0 R: 3 N: 1 D: 0 C: 0 E: 0 Q: 1 G: 0 H: 0 I: 2 L: 0 K: 4 M: 1 F: 1 P: 1 S: 0 T: 0 W: 2 Y: 0 V: 0
Chemical Descriptors
16
C104H167N33O19S1
2215.74
12.72
+7
2.16
-1.612
Conjugated with TAMRA
Lys side chain amine at the C-terminus
L
Amphipathic
Linear
Free
N[C@@H](CCCN=C)C(=O)N[C@@H](CCC(=O)N)C(=O)N[C@@H]([C@@H](C)CC)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H]([C@@H](C)CC)C(=O)N[C@@H](CC1=CN=C(C)/C/1=C\C)C(=O)N[C@@H](Cc1ccccc1)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CC(=O)N)C(=O)N[C@@H](CCCN=C)C(=O)N[C@@H](CCCN=C)C(=O)N[C@@H](CCSC)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CC1=C(C(=NC1)C)CC)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCCN)C(=O)O
Evidence Records 1 records
Evidence 1 Activity

Activity

Cell-penetrating Peptides

Target

By-2 Cells Leaves Of Nicotiana Benthamiana, Arabidopsis Thaliana, Tomato (Solanum Lycopersicum), Poplar (Hybrid Aspen Populus Tremula×Tremuloides Line T89), And Rice (Oryza Sativa).

Source & Reference

CPPsite3.0
CPPsite3

Other

Source Activity Label Source Definition
Cell-penetrating Peptides
CPPsite3.0 experimentally validated cell-penetrating peptide annotation.
Natural residues Linear L Amphipathic
TAMRA dye
In vitro
CCCCSSCCHHHHHHTC
Additional Detail Fields 1 fields
CCCCSSCCHHHHHHTC