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Peptide record

TPDB93125

peptide 6 Cell-penetrating Peptides standard
22 amino acids
Basic Information
3D PDB MODEL
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TPDB93125
peptide 6
Cell-penetrating Peptides
Delivery and barrier-penetrating peptides
CellPPD CellPPD-MOD CPPsite3.0 MLCPP 2.0 Peptipedia PerseuCPP
standard
No
A 22-aa standard natural cell-penetrating peptides peptide sequence curated from CellPPD, CellPPD-MOD, CPPsite3.0, and other sources, with an available 3D structural model.
N-terminal: Conjugated with 6-Carboxyfluorescein (6-Fam)
Sequence
RQARRNRRRALWKTLLKKVLKA
Physicochemical Analysis
C122H221N47O26
DCEGHIMFPSY
R
2762.40
13.10
10
0
9
+10
5.43
-1.200
97.73
Mammalian: 1 hour Yeast: 2 min E.coli: 2 min
5500
199.10
3
Residue Composition
number
3
A
6
R
1
N
0
D
0
C
0
E
1
Q
0
G
0
H
0
I
4
L
4
K
0
M
0
F
0
P
0
S
1
T
1
W
0
Y
1
V
Amino Acid Distribution
A: 3 R: 6 N: 1 D: 0 C: 0 E: 0 Q: 1 G: 0 H: 0 I: 0 L: 4 K: 4 M: 0 F: 0 P: 0 S: 0 T: 1 W: 1 Y: 0 V: 1
Chemical Descriptors
22
C122H221N47O26
2762.40
13.10
+10
5.43
-1.200
Free
L
Amphipathic
Linear
Conjugated with 6-Carboxyfluorescein (6-Fam)
N[C@@H](CCCCN)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](C)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](C)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](C)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](C)C(=O)N[C@@H](C)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CCCCN)C(=O)O
Evidence Records 1 records
Evidence 1 Activity

Activity

Cell-penetrating Peptides

Target

HeLa Cells

Source & Reference

CPPsite3.0
CPPsite3

Other

Source Activity Label Source Definition
Cell-penetrating Peptides
CPPsite3.0 experimentally validated cell-penetrating peptide annotation.
Natural residues Linear L Amphipathic
5(6)-carboxyfluorescein (FAM) dye
450.97 RFU
In vitro
CCCTTCHHHHHHHHTC
Additional Detail Fields 1 fields
CCCTTCHHHHHHHHTC