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Peptide record

TPDB93124

Ara-27 Cell-penetrating Peptides standard
27 amino acids
Basic Information
3D PDB MODEL
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TPDB93124
Ara-27
Cell-penetrating Peptides
Delivery and barrier-penetrating peptides
CPPsite3.0
standard
No
A 27-aa standard natural cell-penetrating peptides peptide sequence curated from CPPsite3.0, with an available 3D structural model.
C-terminal: Conjugated with FITC via Lysine (K)
Sequence
RNQRKTVRCFRCRQAGHWISDCRLKSK
Physicochemical Analysis
C139H234N54O36S3
EMPY
R
3333.91
11.78
10
1
6
+8
7.34
-1.293
43.33
Mammalian: 1 hour Yeast: 2 min E.coli: 2 min
5625
168.72
9
Residue Composition
number
1
A
6
R
1
N
1
D
3
C
0
E
2
Q
1
G
1
H
1
I
1
L
3
K
0
M
1
F
0
P
2
S
1
T
1
W
0
Y
1
V
Amino Acid Distribution
A: 1 R: 6 N: 1 D: 1 C: 3 E: 0 Q: 2 G: 1 H: 1 I: 1 L: 1 K: 3 M: 0 F: 1 P: 0 S: 2 T: 1 W: 1 Y: 0 V: 1
Chemical Descriptors
27
C139H234N54O36S3
3333.91
11.78
+8
7.34
-1.293
Conjugated with FITC via Lysine (K)
L
Hydrophobic
Linear
Free
N[C@@H](C)C(=O)N[C@@H](C)C(=O)N[C@@H](C(C)C)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CC(C)C)C(=O)N1CCC[C@H]1C(=O)N[C@@H](C(C)C)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](C)C(=O)N[C@@H](C)C(=O)N1CCC[C@H]1C(=O)O
Evidence Records 1 records
Evidence 1 Activity

Activity

Cell-penetrating Peptides

Target

Human Dermal Fibroblast (Hdf) And Human Dental Pulp Stem Cells (Hdpsc)

Source & Reference

CPPsite3.0
CPPsite3

Other

Source Activity Label Source Definition
Cell-penetrating Peptides
CPPsite3.0 experimentally validated cell-penetrating peptide annotation.
Natural residues Linear L Hydrophobic
Protein derived
FITC-labeled
Cytoplasm and nucleus
Ara-27 were around 8 to 22 times higher than those of Tat-PTD and MTS in both cells.
In vitro
CCCCCCCCCCCC
Additional Detail Fields 1 fields
CCCCCCCCCCCC