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Peptide record

TPDB93123

Cell-penetrating Peptides Tumor-homing Peptides standard
15 amino acids
Basic Information
3D PDB MODEL
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TPDB93123
Cell-penetrating Peptides Tumor-homing Peptides
Cancer-related peptides Delivery and barrier-penetrating peptides
CellPPD CPPsite3.0 MLCPP 2.0 Peptipedia PerseuCPP TumorHoPe2.0
standard
No
A 15-aa standard natural multi-activity (Cell-penetrating Peptides and Tumor-homing Peptides) peptide sequence curated from CellPPD, CPPsite3.0, MLCPP 2.0, and other sources, with an available 3D structural model.
N-terminal: Cysteine
Sequence
RLYMRYYSPTTRRYG
Physicochemical Analysis
C89H135N27O23S1
ANDCEQHIKFWV
RY
1983.28
10.58
4
0
6
+4
-0.44
-1.447
26.00
Mammalian: 1 hour Yeast: 2 min E.coli: 2 min
5960
300.51
7
Residue Composition
number
0
A
4
R
0
N
0
D
0
C
0
E
0
Q
1
G
0
H
0
I
1
L
0
K
1
M
0
F
1
P
1
S
2
T
0
W
4
Y
0
V
Amino Acid Distribution
A: 0 R: 4 N: 0 D: 0 C: 0 E: 0 Q: 0 G: 1 H: 0 I: 0 L: 1 K: 0 M: 1 F: 0 P: 1 S: 1 T: 2 W: 0 Y: 4 V: 0
Chemical Descriptors
15
C89H135N27O23S1
1983.28
10.58
+4
-0.44
-1.447
Cysteine
Evidence Records 2 records
Evidence 1 Activity

Activity

Tumor-homing Peptides

Target

Homing
Breast cancer

Source & Reference

TumorHoPe2.0
TumorHoPe2
Cancer-Cell-Specific Drug Delivery by a Tumor-Homing CPP-Gossypol Conjugate Employing a Tracelessly Cleavable Linker
2020
Maity SK et al. Chemistry. 2020 Mar 9 26(14):3010-3015

Other

Source Activity Label Source Definition
Tumor-homing Peptides
TumorHoPe2.0 experimentally validated tumor-homing peptide annotation.
-MCF 7.00
Synthetic
Cysteine conjugated at the N-terminus
Evidence 2 Activity

Activity

Tumor-homing Peptides

Target

Homing, Penetrating
Breast cancer

Source & Reference

TumorHoPe2.0
TumorHoPe2
Cancer-Cell-Specific Drug Delivery by a Tumor-Homing CPP-Gossypol Conjugate Employing a Tracelessly Cleavable Linker
2020
Maity S K et al. Chemistry.2020 Mar 9 26(14):3010-3015

Other

Human breast cancer cell line MCF-7
Synthetic
Gossypol
Cell penetrating peptide
Additional Detail Fields 2 fields
Cysteine conjugated at the N-terminus Gossypol
-MCF 7.00 Human breast cancer cell line MCF-7