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Peptide record

TPDB93120

Tumor lineage-homing CPP Cell-penetrating Peptides Tumor-homing Peptides standard
15 amino acids
Basic Information
3D PDB MODEL
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TPDB93120
Tumor lineage-homing CPP
Cell-penetrating Peptides Tumor-homing Peptides
Cancer-related peptides Delivery and barrier-penetrating peptides
CellPPD CPPsite3.0 MLCPP 2.0 Peptipedia PerseuCPP TumorHoPe2.0
standard
No
A 15-aa standard natural multi-activity (Cell-penetrating Peptides and Tumor-homing Peptides) peptide sequence curated from CellPPD, CPPsite3.0, MLCPP 2.0, and other sources, with an available 3D structural model.
Chemical: Nanospheres
Sequence
RLYMRYYSPTTRRYG
Physicochemical Analysis
C89H135N27O23S1
ANDCEQHIKFWV
RY
1983.28
10.58
4
0
6
+4
-0.44
-1.447
26.00
Mammalian: 1 hour Yeast: 2 min E.coli: 2 min
5960
300.51
7
Residue Composition
number
0
A
4
R
0
N
0
D
0
C
0
E
0
Q
1
G
0
H
0
I
1
L
0
K
1
M
0
F
1
P
1
S
2
T
0
W
4
Y
0
V
Amino Acid Distribution
A: 0 R: 4 N: 0 D: 0 C: 0 E: 0 Q: 0 G: 1 H: 0 I: 0 L: 1 K: 0 M: 1 F: 0 P: 1 S: 1 T: 2 W: 0 Y: 4 V: 0
Chemical Descriptors
15
C89H135N27O23S1
1983.28
10.58
+4
-0.44
-1.447
Free
Nanospheres
L
Hydrophilic
Linear
Free
N[C@@H](CCCN=C)C(=O)N[C@@H](CCC(=O)N)C(=O)N[C@@H]([C@@H](C)CC)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H]([C@@H](C)CC)C(=O)N[C@@H](CC1=CN=C(C)/C/1=C\C)C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H](CCC(=O)N)C(=O)N[C@@H](CC(=O)N)C(=O)N[C@@H](CCCN=C)C(=O)N[C@@H](CCCN=C)C(=O)N[C@@H](CCSC)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CC1=CN=C(C)/C/1=C\C)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCCN)C(=O)O
Evidence Records 1 records
Evidence 1 Activity

Activity

Cell-penetrating Peptides

Target

Hepg2 Cells

Source & Reference

CPPsite3.0
CPPsite3

Other

Source Activity Label Source Definition
Cell-penetrating Peptides
CPPsite3.0 experimentally validated cell-penetrating peptide annotation.
Natural residues Linear L Hydrophilic
Taxol via succinic acid (SA) and tripeptide EEG and doxorubicin (Dox)
Cytoplasm and Nuclei
Obvious red fluorescence signals were observed in both the cytoplasm and nuclei of the HepG2 cells.
In vitro
CCCSSSTTCCCTTTTC
Additional Detail Fields 1 fields
CCCSSSTTCCCTTTTC