Back to search

Peptide record

TPDB93106

TAT Cell-penetrating Peptides standard
10 amino acids
Basic Information
3D PDB MODEL
Drag to rotate. Click a residue or atom to inspect it; the selected residue is highlighted in amber.
TPDB93106
TAT
Cell-penetrating Peptides
Delivery and barrier-penetrating peptides
CPPsite3.0
standard
No
A 10-aa standard natural cell-penetrating peptides peptide sequence curated from CPPsite3.0, with an available 3D structural model.
C-terminal: Amidation Chemical: MAL-TEG-(KH)14 micelles N-terminal: Acetylation
Sequence
Ac-RKKRRQRRRC-NH2
Physicochemical Analysis
C56H111N31O12S1
ANDEGHILMFPSTWYV
R
1442.76
12.71
8
0
0
+8
7.18
-3.580
0.00
Mammalian: 1 hour Yeast: 2 min E.coli: 2 min
0
0.00
2
Residue Composition
number
0
A
6
R
0
N
0
D
1
C
0
E
1
Q
0
G
0
H
0
I
0
L
2
K
0
M
0
F
0
P
0
S
0
T
0
W
0
Y
0
V
Amino Acid Distribution
A: 0 R: 6 N: 0 D: 0 C: 1 E: 0 Q: 1 G: 0 H: 0 I: 0 L: 0 K: 2 M: 0 F: 0 P: 0 S: 0 T: 0 W: 0 Y: 0 V: 0
Chemical Descriptors
10
C56H111N31O12S1
1442.76
12.71
+8
7.18
-3.580
Amidation
MAL-TEG-(KH)14 micelles
L
Cationic
Linear
Acetylation
N[C@@H](CS)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCN=C)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](C(C)C)C(=O)O
Evidence Records 1 records
Evidence 1 Activity

Activity

Cell-penetrating Peptides

Target

Seedlings Of Arabidopsis Thaliana

Source & Reference

CPPsite3.0
CPPsite3

Other

Source Activity Label Source Definition
Cell-penetrating Peptides
CPPsite3.0 experimentally validated cell-penetrating peptide annotation.
Natural residues Linear L Cationic
Protein derived
pDNA (p35S-Nluc-tNOS)
BP100-MC appeared to have higher efficacy than Tat-MC, but no significant difference was observed between them
In vitro
CCCCCSCC
Additional Detail Fields 1 fields
CCCCCSCC