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Peptide record

TPDB93092

No.14-12 Cell-penetrating Peptides standard
15 amino acids
Basic Information
3D PDB MODEL
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TPDB93092
No.14-12
Cell-penetrating Peptides
Delivery and barrier-penetrating peptides
CellPPD CPPsite3.0 MLCPP 2.0 Peptipedia PerseuCPP
standard
No
A 15-aa standard natural cell-penetrating peptides peptide sequence curated from CellPPD, CPPsite3.0, MLCPP 2.0, and other sources, with an available 3D structural model.
N-terminal: Conjugation with fluorescein
Sequence
RAWMRWYSPTTRRYG
Physicochemical Analysis
C90H131N29O21S1
NDCEQHILKFV
R
1987.27
11.94
4
0
6
+4
-1.87
-1.527
6.67
Mammalian: 1 hour Yeast: 2 min E.coli: 2 min
13980
703.48
5
Residue Composition
number
1
A
4
R
0
N
0
D
0
C
0
E
0
Q
1
G
0
H
0
I
0
L
0
K
1
M
0
F
1
P
1
S
2
T
2
W
2
Y
0
V
Amino Acid Distribution
A: 1 R: 4 N: 0 D: 0 C: 0 E: 0 Q: 0 G: 1 H: 0 I: 0 L: 0 K: 0 M: 1 F: 0 P: 1 S: 1 T: 2 W: 2 Y: 2 V: 0
Chemical Descriptors
15
C90H131N29O21S1
1987.27
11.94
+4
-1.87
-1.527
Free
L
Amphipathic
Linear
Conjugation with fluorescein
N[C@@H](CCCN=C)C(=O)N[C@@H](C)C(=O)N[C@@H](CC1=C(C(=NC1)C)CC)C(=O)N[C@@H](CCSC)C(=O)N[C@@H](CCCN=C)C(=O)N[C@@H](CC1=C(C(=NC1)C)CC)C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H](CO)C(=O)N1CCC[C@H]1C(=O)N[C@@H]([C@@H](C)O)C(=O)N[C@@H]([C@@H](C)O)C(=O)N[C@@H](CCCN=C)C(=O)N[C@@H](CCCN=C)C(=O)N[C@@H](Cc1ccccc1)C(=O)NCC(=O)O
Evidence Records 1 records
Evidence 1 Activity

Activity

Cell-penetrating Peptides

Target

CHO

Source & Reference

CPPsite3.0
CPPsite3

Other

Source Activity Label Source Definition
Cell-penetrating Peptides
CPPsite3.0 experimentally validated cell-penetrating peptide annotation.
Natural residues Linear L Amphipathic
Synthetic
Fluorophore (fluorescein)
Higher than Peptide 14 and equal to peptide 14-1
In vitro
CCCCCSSSCGGGSCC
Additional Detail Fields 1 fields
CCCCCSSSCGGGSCC