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Peptide record

TPDB93074

PreS2-TLM Blood-Brain Barrier Cell-penetrating Peptides standard
12 amino acids
Basic Information
3D PDB MODEL
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TPDB93074
PreS2-TLM
Blood-Brain Barrier Cell-penetrating Peptides
Delivery and barrier-penetrating peptides
BBPpredict CellPPD CPPsite3.0 MLCPP 2.0 Peptipedia
standard
No
A 12-aa standard natural multi-activity (Blood-Brain Barrier and Cell-penetrating Peptides) peptide sequence curated from BBPpredict, CellPPD, CPPsite3.0, and other sources, with an available 3D structural model.
N-terminal: Conjugated with Cyanine5.5 (Cy5.5)
Sequence
PLSSIFSRIGDP
Physicochemical Analysis
C58H93N15O18
ANCEQHKMTWYV
S
1288.47
6.78
1
1
4
-0
1.03
0.133
97.50
Mammalian: >20 hour Yeast: >20 hour E.coli: ?
0
0.00
3
Residue Composition
number
0
A
1
R
0
N
1
D
0
C
0
E
0
Q
1
G
0
H
2
I
1
L
0
K
0
M
1
F
2
P
3
S
0
T
0
W
0
Y
0
V
Amino Acid Distribution
A: 0 R: 1 N: 0 D: 1 C: 0 E: 0 Q: 0 G: 1 H: 0 I: 2 L: 1 K: 0 M: 0 F: 1 P: 2 S: 3 T: 0 W: 0 Y: 0 V: 0
Chemical Descriptors
12
C58H93N15O18
1288.47
6.78
-0
1.03
0.133
Free
L
Amphipathic
Linear
Conjugated with Cyanine5.5 (Cy5.5)
N[C@@H](C)C(=O)N[C@@H](CC1=CN=C(C)/C/1=C\C)C(=O)N[C@@H](CCCN=C)C(=O)N[C@@H](CCCN=C)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](C)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](C)C(=O)N1CCC[C@H]1C(=O)N[C@@H](C)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](C)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](C(C)C)C(=O)O
Evidence Records 1 records
Evidence 1 Activity

Activity

Cell-penetrating Peptides

Target

Primary Human Astrocytes

Source & Reference

CPPsite3.0
CPPsite3

Other

Source Activity Label Source Definition
Cell-penetrating Peptides
CPPsite3.0 experimentally validated cell-penetrating peptide annotation.
Natural residues Linear L Amphipathic
Protein derived
Cy5.5 dye
In vitro
CTHHHHSSCCTTSCCCC
Additional Detail Fields 1 fields
CTHHHHSSCCTTSCCCC