Back to search

Peptide record

TPDB93070

FITC-NS Cell-penetrating Peptides standard
18 amino acids
Basic Information
3D PDB MODEL
Drag to rotate. Click a residue or atom to inspect it; the selected residue is highlighted in amber.
TPDB93070
FITC-NS
Cell-penetrating Peptides
Delivery and barrier-penetrating peptides
CellPPD-MOD CPPsite3.0 MLCPP 2.0 Peptipedia
standard
No
A 18-aa standard natural cell-penetrating peptides peptide sequence curated from CellPPD-MOD, CPPsite3.0, MLCPP 2.0, and other sources, with an available 3D structural model.
C-terminal: Amidation Chemical: Spacer 6-aminohexanoic acid (Ahx)
Sequence
PKKKRKVWKLLQQFFGLM-NH2
Physicochemical Analysis
C110H179N29O21S1
ANDCEHISTY
K
2275.87
11.85
6
0
8
+6
1.43
-0.600
81.11
Mammalian: >20 hour Yeast: >20 hour E.coli: ?
5500
241.67
2
Residue Composition
number
0
A
1
R
0
N
0
D
0
C
0
E
2
Q
1
G
0
H
0
I
3
L
5
K
1
M
2
F
1
P
0
S
0
T
1
W
0
Y
1
V
Amino Acid Distribution
A: 0 R: 1 N: 0 D: 0 C: 0 E: 0 Q: 2 G: 1 H: 0 I: 0 L: 3 K: 5 M: 1 F: 2 P: 1 S: 0 T: 0 W: 1 Y: 0 V: 1
Chemical Descriptors
18
C110H179N29O21S1
2275.87
11.85
+6
1.43
-0.600
Amidation
Spacer 6-aminohexanoic acid (Ahx)
L
Cationic
Linear
Free
N1CCC[C@H]1C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCN=C)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](C(C)C)C(=O)N[C@@H](CC1=CN=C(C)/C/1=C\C)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CCC(=O)N)C(=O)N[C@@H](CCC(=O)N)C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H](Cc1ccccc1)C(=O)NCC(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CCSC)C(=O)O
Evidence Records 1 records
Evidence 1 Activity

Activity

Cell-penetrating Peptides

Target

HeLa

Source & Reference

CPPsite3.0
CPPsite3

Other

Source Activity Label Source Definition
Cell-penetrating Peptides
CPPsite3.0 experimentally validated cell-penetrating peptide annotation.
Natural residues Linear L Cationic
Synthetic
Fluorophore (FITC)
Nucleus
Higher Uptake
Caspase-independent pathway
In vitro
CGGGGGGGHHHHHHHSCC
Additional Detail Fields 1 fields
CGGGGGGGHHHHHHHSCC