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Peptide record

TPDB93069

peptide 13 Cell-penetrating Peptides standard
20 amino acids
Basic Information
3D PDB MODEL
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TPDB93069
peptide 13
Cell-penetrating Peptides
Delivery and barrier-penetrating peptides
CellPPD CellPPD-MOD CPPsite3.0 MLCPP 2.0 Peptipedia PerseuCPP
standard
No
A 20-aa standard natural cell-penetrating peptides peptide sequence curated from CellPPD, CellPPD-MOD, CPPsite3.0, and other sources, with an available 3D structural model.
N-terminal: Conjugated with 6-Carboxyfluorescein (6-Fam)
Sequence
PKKKRKVALWKTLLKKVLKA
Physicochemical Analysis
C114H206N32O22
NDCEQGHIMFSY
K
2377.09
11.97
9
0
9
+9
5.03
-0.585
117.00
Mammalian: >20 hour Yeast: >20 hour E.coli: ?
5500
231.38
1
Residue Composition
number
2
A
1
R
0
N
0
D
0
C
0
E
0
Q
0
G
0
H
0
I
4
L
8
K
0
M
0
F
1
P
0
S
1
T
1
W
0
Y
2
V
Amino Acid Distribution
A: 2 R: 1 N: 0 D: 0 C: 0 E: 0 Q: 0 G: 0 H: 0 I: 0 L: 4 K: 8 M: 0 F: 0 P: 1 S: 0 T: 1 W: 1 Y: 0 V: 2
Chemical Descriptors
20
C114H206N32O22
2377.09
11.97
+9
5.03
-0.585
Free
L
Amphipathic
Linear
Conjugated with 6-Carboxyfluorescein (6-Fam)
N[C@@H](Cc1ccccc1)C(=O)N[C@@H]([C@@H](C)O)C(=O)N[C@@H](C)C(=O)N[C@@H]([C@@H](C)CC)C(=O)N[C@@H](C)C(=O)N[C@@H](CC1=C(C(=NC1)C)CC)C(=O)N[C@@H](C(C)C)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](C)C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H]([C@@H](C)CC)C(=O)N[C@@H](CCCN=C)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CCCN=C)C(=O)N[C@@H](CCCCN)C(=O)O
Evidence Records 1 records
Evidence 1 Activity

Activity

Cell-penetrating Peptides

Target

HeLa Cells

Source & Reference

CPPsite3.0
CPPsite3

Other

Source Activity Label Source Definition
Cell-penetrating Peptides
CPPsite3.0 experimentally validated cell-penetrating peptide annotation.
Natural residues Linear L Amphipathic
5(6)-carboxyfluorescein (FAM) dye
390.81 RFU
In vitro
CCSSHHHHHHHTTTTC
Additional Detail Fields 1 fields
CCSSHHHHHHHTTTTC