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Peptide record

TPDB93055

FAM-gHo Cell-penetrating Peptides Tumor-homing Peptides standard
12 amino acids
Basic Information
3D PDB MODEL
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TPDB93055
FAM-gHo
Cell-penetrating Peptides Tumor-homing Peptides
Cancer-related peptides Delivery and barrier-penetrating peptides
CellPPD-MOD CPPsite3.0 Peptipedia TumorHoPe2.0
standard
No
A 12-aa standard natural multi-activity (Cell-penetrating Peptides and Tumor-homing Peptides) peptide sequence curated from CellPPD-MOD, CPPsite3.0, Peptipedia, and other sources, with an available 3D structural model.
C-terminal: Amidation N-terminal: Conjugation with 5(6)-Carboxyfluorescein
Sequence
NHQQQNPHQPPM-NH2
Physicochemical Analysis
C60H90N22O19S1
ARDCEGILKFSTWYV
Q
1455.57
8.00
2
0
1
+0
6.20
-2.525
0.00
Mammalian: 1.4 hour Yeast: 3 min E.coli: >10 hour
0
0.00
6
Residue Composition
number
0
A
0
R
2
N
0
D
0
C
0
E
4
Q
0
G
2
H
0
I
0
L
0
K
1
M
0
F
3
P
0
S
0
T
0
W
0
Y
0
V
Amino Acid Distribution
A: 0 R: 0 N: 2 D: 0 C: 0 E: 0 Q: 4 G: 0 H: 2 I: 0 L: 0 K: 0 M: 1 F: 0 P: 3 S: 0 T: 0 W: 0 Y: 0 V: 0
Chemical Descriptors
12
C60H90N22O19S1
1455.57
8.00
+0
6.20
-2.525
Amidation
L
Linear
Conjugation with 5(6)-Carboxyfluorescein
N[C@@H](CC(=O)N)C(=O)N[C@@H](Cc1[nH]cnc1)C(=O)N[C@@H](CCC(=O)N)C(=O)N[C@@H](CCC(=O)N)C(=O)N[C@@H](CCC(=O)N)C(=O)N[C@@H](CC(=O)N)C(=O)N1CCC[C@H]1C(=O)N[C@@H](Cc1[nH]cnc1)C(=O)N[C@@H](CCC(=O)N)C(=O)N1CCC[C@H]1C(=O)N1CCC[C@H]1C(=O)N[C@@H](CCSC)C(=O)O
Evidence Records 1 records
Evidence 1 Activity

Activity

Cell-penetrating Peptides

Target

HEK 293, human glioma, U87 MG and HeLa

Assay & Model

Female nude mice
Female nude mice

Source & Reference

CPPsite3.0
CPPsite3

Other

Source Activity Label Source Definition
Cell-penetrating Peptides
CPPsite3.0 experimentally validated cell-penetrating peptide annotation.
Natural residues Linear L
Synthetic
Fluorophore [5(6)-carboxyfluorescein (FAM)]
In vitro and in vivo
CCCCCCCCCC
Additional Detail Fields 1 fields
CCCCCCCCCC