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Peptide record

TPDB93054

ZF5 3 Cell-penetrating Peptides standard
28 amino acids
Basic Information
3D PDB MODEL
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TPDB93054
ZF5 3
Cell-penetrating Peptides
Delivery and barrier-penetrating peptides
CPPsite3.0
standard
No
A 28-aa standard natural cell-penetrating peptides peptide sequence curated from CPPsite3.0, with an available 3D structural model.
N-terminal: Conjugated with Snap-Tag
Sequence
MYSCNVCGKAFVLSRHLNRHLRVHRRAT
Physicochemical Analysis
C142H234N52O35S3
DEQIPW
R
3325.93
11.83
9
0
11
+6
4.58
-0.346
80.00
Mammalian: 30 hour Yeast: >20 hour E.coli: >10 hour
1615
48.56
8
Residue Composition
number
2
A
5
R
2
N
0
D
2
C
0
E
0
Q
1
G
3
H
0
I
3
L
1
K
1
M
1
F
0
P
2
S
1
T
0
W
1
Y
3
V
Amino Acid Distribution
A: 2 R: 5 N: 2 D: 0 C: 2 E: 0 Q: 0 G: 1 H: 3 I: 0 L: 3 K: 1 M: 1 F: 1 P: 0 S: 2 T: 1 W: 0 Y: 1 V: 3
Chemical Descriptors
28
C142H234N52O35S3
3325.93
11.83
+6
4.58
-0.346
Free
L
Linear
Conjugated with Snap-Tag
NCC(=O)N[C@@H](Cc1ccccc1)C(=O)NCC(=O)N[C@@H](CCCN=C)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCN=C)C(=O)N[C@@H](CCCN=C)C(=O)N[C@@H](CCC(=O)N)C(=O)N[C@@H](CCCN=C)C(=O)N[C@@H](CCCN=C)C(=O)N[C@@H](CCCN=C)C(=O)N[C@@H](Cc1ccccc1)C(=O)N1CCC[C@H]1C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H](CC(=O)O)C(=O)N[C@@H](C(C)C)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CC(=O)O)C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H](C)C(=O)N[C@@H](CCC(=O)O)C(=O)N[C@@H](Cc1[nH]cnc1)C(=O)N[C@@H]([C@@H](C)O)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](C)C(=O)N[C@@H](CC(=O)O)C(=O)N[C@@H](C(C)C)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CCCN=C)C(=O)N[C@@H](Cc1[nH]cnc1)C(=O)N[C@@H](C(C)C)C(=O)N[C@@H](CCC(=O)O)C(=O)N[C@@H]([C@@H](C)O)C(=O)N[C@@H](CCC(=O)O)C(=O)N[C@@H](C(C)C)C(=O)N[C@@H](CC(=O)O)C(=O)NCC(=O)N[C@@H](CCCN=C)C(=O)N[C@@H](CCCN=C)C(=O)N[C@@H](CO)C(=O)O
Evidence Records 1 records
Evidence 1 Activity

Activity

Cell-penetrating Peptides

Target

Saos-2 Cells , HeLa And Sk-Hep-1 Cells

Source & Reference

CPPsite3.0
CPPsite3

Other

Source Activity Label Source Definition
Cell-penetrating Peptides
CPPsite3.0 experimentally validated cell-penetrating peptide annotation.
Natural residues Linear L
Protein derived
Rho-labeled SNAP-tag (enzyme)
Cytosol
17-fold increase relative to cells treated with SNAP-Rho
Endocytosis
In vitro
CCCSSSTTSCCCCSSCCSSSSSCSSGGGCSSSSSCCTTC
Additional Detail Fields 1 fields
CCCSSSTTSCCCCSSCCSSSSSCSSGGGCSSSSSCCTTC