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Peptide record

TPDB93046

Bovine Prp (1-30) Cell-penetrating Peptides standard
30 amino acids
Basic Information
3D PDB MODEL
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TPDB93046
Bovine Prp (1-30)
Cell-penetrating Peptides
Delivery and barrier-penetrating peptides
CellPPD CellPPD-MOD CPPsite3.0 MLCPP 2.0 Peptipedia PerseuCPP
standard
No
A 30-aa standard natural cell-penetrating peptides peptide sequence curated from CellPPD, CellPPD-MOD, CPPsite3.0, and other sources, with an available 3D structural model.
C-terminal: Amidation N-terminal: Conjugation with fluorescein
Sequence
MVKSKIGSWILVLFVAMWSDVGLCKKRPKP-NH2
Physicochemical Analysis
C160H262N40O36S3
NEQHTY
K
3418.27
10.70
6
1
15
+5
0.58
0.413
107.00
Mammalian: 30 hour Yeast: >20 hour E.coli: >10 hour
11000
321.80
4
Residue Composition
number
1
A
1
R
0
N
1
D
1
C
0
E
0
Q
2
G
0
H
2
I
3
L
5
K
2
M
1
F
2
P
3
S
0
T
2
W
0
Y
4
V
Amino Acid Distribution
A: 1 R: 1 N: 0 D: 1 C: 1 E: 0 Q: 0 G: 2 H: 0 I: 2 L: 3 K: 5 M: 2 F: 1 P: 2 S: 3 T: 0 W: 2 Y: 0 V: 4
Chemical Descriptors
30
C160H262N40O36S3
3418.27
10.70
+5
0.58
0.413
Amidation
L
Amphipathic
Linear
Conjugation with fluorescein
N[C@@H](CCSC)C(=O)N[C@@H](C(C)C)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CO)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H]([C@@H](C)CC)C(=O)NCC(=O)N[C@@H](CO)C(=O)N[C@@H](CC1=C(C(=NC1)C)CC)C(=O)N[C@@H]([C@@H](C)CC)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](C(C)C)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H](C(C)C)C(=O)N[C@@H](C)C(=O)N[C@@H](CCSC)C(=O)N[C@@H](CC1=CN=C(C)/C/1=C\C)C(=O)N[C@@H](CO)C(=O)N[C@@H](CC(=O)O)C(=O)N[C@@H](C(C)C)C(=O)NCC(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CS)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCN=C)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CCCCN)C(=O)N1CCC[C@H]1C(=O)O
Evidence Records 1 records
Evidence 1 Activity

Activity

Cell-penetrating Peptides

Target

Human bowes melanoma, N1e neuroblastoma and N2A cells

Source & Reference

CPPsite3.0
CPPsite3

Other

Source Activity Label Source Definition
Cell-penetrating Peptides
CPPsite3.0 experimentally validated cell-penetrating peptide annotation.
Natural residues Linear L Amphipathic
Protein derived
Fluorophore (fluorescein)
Probably perinuclearly and in the cytosol
In vitro
CCCCCCCCSSTHHHHTTTTSCTTSCCCCCC
Additional Detail Fields 1 fields
CCCCCCCCSSTHHHHTTTTSCTTSCCCCCC