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Peptide record

TPDB93044

Cytcox-(KH)9 Cell-penetrating Peptides standard
30 amino acids
Basic Information
3D PDB MODEL
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TPDB93044
Cytcox-(KH)9
Cell-penetrating Peptides
Delivery and barrier-penetrating peptides
CPPsite3.0
standard
No
A 30-aa standard natural cell-penetrating peptides peptide sequence curated from CPPsite3.0, with an available 3D structural model.
C-terminal: Amidation Chemical: Micelles
Sequence
MLSLRQSIRFFKKHKHKHKHKHKHKHKHKH-NH2
Physicochemical Analysis
C178H287N65O34S1
ANDCEGPTWYV
K
3913.71
12.49
21
0
6
+13
17.08
-2.077
39.00
Mammalian: 30 hour Yeast: >20 hour E.coli: >10 hour
0
0.00
3
Residue Composition
number
0
A
2
R
0
N
0
D
0
C
0
E
1
Q
0
G
9
H
1
I
2
L
10
K
1
M
2
F
0
P
2
S
0
T
0
W
0
Y
0
V
Amino Acid Distribution
A: 0 R: 2 N: 0 D: 0 C: 0 E: 0 Q: 1 G: 0 H: 9 I: 1 L: 2 K: 10 M: 1 F: 2 P: 0 S: 2 T: 0 W: 0 Y: 0 V: 0
Chemical Descriptors
30
C178H287N65O34S1
3913.71
12.49
+13
17.08
-2.077
Amidation
Micelles
L
Linear
Free
N[C@@H](CCSC)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CO)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CCCN=C)C(=O)N[C@@H](CCC(=O)N)C(=O)N[C@@H](CO)C(=O)N[C@@H]([C@@H](C)CC)C(=O)N[C@@H](CCCN=C)C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CS)C(=O)O
Evidence Records 1 records
Evidence 1 Activity

Activity

Cell-penetrating Peptides

Assay & Model

Arabidopsis thaliana (A. thaliana)
Arabidopsis thaliana (A. thaliana)

Source & Reference

CPPsite3.0
CPPsite3

Other

Source Activity Label Source Definition
Cell-penetrating Peptides
CPPsite3.0 experimentally validated cell-penetrating peptide annotation.
Natural residues Linear L
Synthetic
pDNA(pDONR-Cox2-RLuc, pATMTTF1, pDONR-35S-RLuc, and pDONR-35S-GFP)
For Cytcox-(KH)9/pDNA complex (nuc-GFP),GFP fluorescence was not observed in root cells.
Direct translocation
In vivo
CCCTTTSSCCCCC
Additional Detail Fields 1 fields
CCCTTTSSCCCCC