Peptide record

TPDB93043

TCTP-PTD Cell-penetrating Peptides standard
10 amino acids
Basic Information
3D PDB MODEL
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TPDB93043
TCTP-PTD
Cell-penetrating Peptides
Delivery and barrier-penetrating peptides
CellPPD CellPPD-MOD CPPsite3.0 MLCPP 2.0 Peptipedia PerseuCPP
standard
No
A 10-aa standard natural cell-penetrating peptides peptide sequence curated from CellPPD, CellPPD-MOD, CPPsite3.0, and other sources, with an available 3D structural model.
C-terminal: Conjugated with mCherry protein
Sequence
MIIYRDLISH
Physicochemical Analysis
C57H93N15O15S1
ANCEQGKFPTWV
I
1260.52
7.77
2
1
6
+0
0.47
0.590
156.00
Mammalian: 30 hour Yeast: >20 hour E.coli: >10 hour
1490
118.21
2
Residue Composition
number
0
A
1
R
0
N
1
D
0
C
0
E
0
Q
0
G
1
H
3
I
1
L
0
K
1
M
0
F
0
P
1
S
0
T
0
W
1
Y
0
V
Amino Acid Distribution
A: 0 R: 1 N: 0 D: 1 C: 0 E: 0 Q: 0 G: 0 H: 1 I: 3 L: 1 K: 0 M: 1 F: 0 P: 0 S: 1 T: 0 W: 0 Y: 1 V: 0
Chemical Descriptors
10
C57H93N15O15S1
1260.52
7.77
+0
0.47
0.590
Conjugated with mCherry protein
L
Hydrophobic
Linear
Free
N[C@@H](CCSC)C(=O)N[C@@H]([C@@H](C)CC)C(=O)N[C@@H]([C@@H](C)CC)C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H](CCCN=C)C(=O)N[C@@H](CC(=O)O)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H]([C@@H](C)CC)C(=O)N[C@@H](CO)C(=O)N[C@@H](CC1=NC=NC1)C(=O)O
Evidence Records 1 records
Evidence 1 Activity

Activity

Cell-penetrating Peptides

Target

Mouse Oocytes

Source & Reference

CPPsite3.0
CPPsite3

Other

Source Activity Label Source Definition
Cell-penetrating Peptides
CPPsite3.0 experimentally validated cell-penetrating peptide annotation.
Natural residues Linear L Hydrophobic
Protein derived
Fluorescence dye-labeled siRNAs targeting cyclin B1
Cytoplasm
TCTP-mCherry is internalized into the cytoplasm of oocytes afer passing through the ZP.
In vitro
CCCCCGGGC
Additional Detail Fields 1 fields
CCCCCGGGC