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Peptide record

TPDB93027

peptide 10 Cell-penetrating Peptides standard
24 amino acids
Basic Information
3D PDB MODEL
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TPDB93027
peptide 10
Cell-penetrating Peptides
Delivery and barrier-penetrating peptides
CellPPD CellPPD-MOD CPPsite3.0 Peptipedia PerseuCPP
standard
No
A 24-aa standard natural cell-penetrating peptides peptide sequence curated from CellPPD, CellPPD-MOD, CPPsite3.0, and other sources, with an available 3D structural model.
N-terminal: Conjugated with 6-Carboxyfluorescein (6-Fam)
Sequence
LNSAGYLLGKINLKALAALAKKIL
Physicochemical Analysis
C117H206N30O29
RDCEQHMFPTWV
L
2497.11
10.64
4
0
15
+4
-1.38
0.796
167.08
Mammalian: 5.5 hour Yeast: 3 min E.coli: 2 min
1490
59.67
4
Residue Composition
number
5
A
0
R
2
N
0
D
0
C
0
E
0
Q
2
G
0
H
2
I
7
L
4
K
0
M
0
F
0
P
1
S
0
T
0
W
1
Y
0
V
Amino Acid Distribution
A: 5 R: 0 N: 2 D: 0 C: 0 E: 0 Q: 0 G: 2 H: 0 I: 2 L: 7 K: 4 M: 0 F: 0 P: 0 S: 1 T: 0 W: 0 Y: 1 V: 0
Chemical Descriptors
24
C117H206N30O29
2497.11
10.64
+4
-1.38
0.796
Free
L
Amphipathic
Linear
Conjugated with 6-Carboxyfluorescein (6-Fam)
N[C@@H](CC(C)C)C(=O)N[C@@H]([C@@H](C)CC)C(=O)N[C@@H](CCCN=C)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CC1=C(C(=NC1)C)CC)C(=O)N[C@@H](CO)C(=O)N[C@@H](Cc1[nH]cnc1)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H]([C@@H](C)CC)C(=O)N[C@@H](Cc1[nH]cnc1)C(=O)N[C@@H]([C@@H](C)CC)C(=O)N[C@@H](CC1=CN=C(C)/C/1=C\C)C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H](CCC(=O)N)C(=O)N[C@@H](CC(=O)N)C(=O)N[C@@H](CCCN=C)C(=O)N[C@@H](CCCN=C)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CC1=C(C(=NC1)C)CC)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCCN)C(=O)O
Evidence Records 1 records
Evidence 1 Activity

Activity

Cell-penetrating Peptides

Target

HeLa Cells

Source & Reference

CPPsite3.0
CPPsite3

Other

Source Activity Label Source Definition
Cell-penetrating Peptides
CPPsite3.0 experimentally validated cell-penetrating peptide annotation.
Natural residues Linear L Amphipathic
5(6)-carboxyfluorescein (FAM) dye
422.13 RFU
In vitro
CCTTTSCCSSSCCCSCSSSCC
Additional Detail Fields 1 fields
CCTTTSCCSSSCCCSCSSSCC