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Peptide record

TPDB93010

EB1 Cell-penetrating Peptides standard
23 amino acids
Basic Information
3D PDB MODEL
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TPDB93010
EB1
Cell-penetrating Peptides
Delivery and barrier-penetrating peptides
CellPPD CellPPD-MOD CPPsite3.0 Peptipedia PerseuCPP
standard
No
A 23-aa standard natural cell-penetrating peptides peptide sequence curated from CellPPD, CellPPD-MOD, CPPsite3.0, and other sources, with an available 3D structural model.
Chemical: (HSA) nanoparticles
Sequence
LIRLWSHLIHIWFQNRRLKWKKK
Physicochemical Analysis
C150H235N45O27
ADCEGMPTYV
LK
3100.80
12.72
9
0
11
+7
-0.41
-0.630
118.70
Mammalian: 5.5 hour Yeast: 3 min E.coli: 2 min
16500
532.12
3
Residue Composition
number
0
A
3
R
1
N
0
D
0
C
0
E
1
Q
0
G
2
H
3
I
4
L
4
K
0
M
1
F
0
P
1
S
0
T
3
W
0
Y
0
V
Amino Acid Distribution
A: 0 R: 3 N: 1 D: 0 C: 0 E: 0 Q: 1 G: 0 H: 2 I: 3 L: 4 K: 4 M: 0 F: 1 P: 0 S: 1 T: 0 W: 3 Y: 0 V: 0
Chemical Descriptors
23
C150H235N45O27
3100.80
12.72
+7
-0.41
-0.630
Free
(HSA) nanoparticles
L
Amphipathic
Linear
Free
NCC(=O)N[C@@H](CCCN=C)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCN=C)C(=O)N[C@@H](CCCN=C)C(=O)N[C@@H](CCC(=O)N)C(=O)N[C@@H](CCCN=C)C(=O)N[C@@H](CCCN=C)C(=O)N[C@@H](CCCN=C)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CCC(=O)N)C(=O)O
Evidence Records 1 records
Evidence 1 Activity

Activity

Cell-penetrating Peptides

Target

Hek 293T Cells

Source & Reference

CPPsite3.0
CPPsite3

Other

Source Activity Label Source Definition
Cell-penetrating Peptides
CPPsite3.0 experimentally validated cell-penetrating peptide annotation.
Natural residues Linear L Amphipathic
Synthetic
Plasmid (pmCherry-N1)
Cytosol
HSA-plasmid-EB1 caused an increased transfection efficiency of 40.1+- 10.7%.
In vitro
CCCCCCCCCCCC
Additional Detail Fields 1 fields
CCCCCCCCCCCC