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Peptide record

TPDB92986

Peptide 1 (CPP74) Cell-penetrating Peptides standard
12 amino acids
Basic Information
3D PDB MODEL
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TPDB92986
Peptide 1 (CPP74)
Cell-penetrating Peptides
Delivery and barrier-penetrating peptides
CellPPD CPPsite3.0 MLCPP 2.0 Peptipedia
standard
No
A 12-aa standard natural cell-penetrating peptides peptide sequence curated from CellPPD, CPPsite3.0, MLCPP 2.0, and other sources, with an available 3D structural model.
C-terminal: Conjugated with TAMRA
Sequence
KRIIQRILSRNS
Physicochemical Analysis
C63H118N24O17
ADCEGHMFPTWYV
RI
1483.78
12.71
4
0
4
+4
3.19
-0.725
130.00
Mammalian: 1.3 hour Yeast: 3 min E.coli: 2 min
0
0.00
4
Residue Composition
number
0
A
3
R
1
N
0
D
0
C
0
E
1
Q
0
G
0
H
3
I
1
L
1
K
0
M
0
F
0
P
2
S
0
T
0
W
0
Y
0
V
Amino Acid Distribution
A: 0 R: 3 N: 1 D: 0 C: 0 E: 0 Q: 1 G: 0 H: 0 I: 3 L: 1 K: 1 M: 0 F: 0 P: 0 S: 2 T: 0 W: 0 Y: 0 V: 0
Chemical Descriptors
12
C63H118N24O17
1483.78
12.71
+4
3.19
-0.725
Conjugated with TAMRA
L
Linear
Free
N[C@@H](CCC(=O)O)C(=O)N[C@@H](C)C(=O)N[C@@H](CCCN=C)C(=O)N1CCC[C@H]1C(=O)N[C@@H](C)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H]([C@@H](C)O)C(=O)N[C@@H](CO)C(=O)N[C@@H](CCCN=C)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CCCN=C)C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H]([C@@H](C)CC)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CCCCN)C(=O)O
Evidence Records 1 records
Evidence 1 Activity

Activity

Cell-penetrating Peptides

Target

E. Coli Dh5Α

Source & Reference

CPPsite3.0
CPPsite3

Other

Source Activity Label Source Definition
Cell-penetrating Peptides
CPPsite3.0 experimentally validated cell-penetrating peptide annotation.
Natural residues Linear L
TAMRA dye
Cytoplasm
Penetration efficiency- 321.591851233333A.U.
In vitro
CCSTTCTHHHHTCCCC
Additional Detail Fields 1 fields
CCSTTCTHHHHTCCCC