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Peptide record

TPDB92974

cys(Npys)-(BP100)2K8 Cell-penetrating Peptides standard
30 amino acids
Basic Information
3D PDB MODEL
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TPDB92974
cys(Npys)-(BP100)2K8
Cell-penetrating Peptides
Delivery and barrier-penetrating peptides
CPPsite3.0
standard
No
A 30-aa standard natural cell-penetrating peptides peptide sequence curated from CPPsite3.0, with an available 3D structural model.
Chemical: Nanoparticle N-terminal: Addition of Cysteine
Sequence
KKLFKKILKYLKKLFKKILKYLKKKKKKKK
Physicochemical Analysis
C192H342N48O33
ARNDCEQGHMPSTWV
K
3851.13
11.23
18
0
12
+18
9.70
-1.180
104.00
Mammalian: 1.3 hour Yeast: 3 min E.coli: 2 min
2980
77.38
2
Residue Composition
number
0
A
0
R
0
N
0
D
0
C
0
E
0
Q
0
G
0
H
2
I
6
L
18
K
0
M
2
F
0
P
0
S
0
T
0
W
2
Y
0
V
Amino Acid Distribution
A: 0 R: 0 N: 0 D: 0 C: 0 E: 0 Q: 0 G: 0 H: 0 I: 2 L: 6 K: 18 M: 0 F: 2 P: 0 S: 0 T: 0 W: 0 Y: 2 V: 0
Chemical Descriptors
30
C192H342N48O33
3851.13
11.23
+18
9.70
-1.180
Free
Nanoparticle
L
Linear
Addition of Cysteine
N[C@@H](CCCN=C)C(=O)N[C@@H](CCCN=C)C(=O)N[C@@H](CCCN=C)C(=O)N[C@@H](CCCN=C)C(=O)N[C@@H](CCCN=C)C(=O)N[C@@H](CCCN=C)C(=O)N[C@@H](CCCN=C)C(=O)N[C@@H](CCCN=C)C(=O)N[C@@H](CCCN=C)C(=O)O
Evidence Records 1 records
Evidence 1 Activity

Activity

Cell-penetrating Peptides

Target

Wheat Microspore Cells And Haploid Embryos

Source & Reference

CPPsite3.0
CPPsite3

Other

Source Activity Label Source Definition
Cell-penetrating Peptides
CPPsite3.0 experimentally validated cell-penetrating peptide annotation.
Natural residues Linear L
ZFN monomers
Cytoplasm and nucleus
10-fold enrichment of indels at the IPK1 locus in subgenome A for microspores treated with ZFN-(BP100)2K8 as compared to control.
In vitro
CCCCCCCCC
Additional Detail Fields 1 fields
CCCCCCCCC