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Peptide record

TPDB92970

M867 Cell-penetrating Peptides standard
16 amino acids
Basic Information
3D PDB MODEL
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TPDB92970
M867
Cell-penetrating Peptides
Delivery and barrier-penetrating peptides
CellPPD CellPPD-MOD CPPsite3.0 MLCPP 2.0 Peptipedia PerseuCPP
standard
No
A 16-aa standard natural cell-penetrating peptides peptide sequence curated from CellPPD, CellPPD-MOD, CPPsite3.0, and other sources, with an available 3D structural model.
C-terminal: Conjugated with TAMRA Chemical: Lys side chain amine at the C-terminus
Sequence
KKICTRKPRFMSAWAQ
Physicochemical Analysis
C87H143N27O20S2
NDEGHLYV
K
1951.38
11.56
5
0
6
+5
1.79
-0.806
36.88
Mammalian: 1.3 hour Yeast: 3 min E.coli: 2 min
5500
281.85
4
Residue Composition
number
2
A
2
R
0
N
0
D
1
C
0
E
1
Q
0
G
0
H
1
I
0
L
3
K
1
M
1
F
1
P
1
S
1
T
1
W
0
Y
0
V
Amino Acid Distribution
A: 2 R: 2 N: 0 D: 0 C: 1 E: 0 Q: 1 G: 0 H: 0 I: 1 L: 0 K: 3 M: 1 F: 1 P: 1 S: 1 T: 1 W: 1 Y: 0 V: 0
Chemical Descriptors
16
C87H143N27O20S2
1951.38
11.56
+5
1.79
-0.806
Conjugated with TAMRA
Lys side chain amine at the C-terminus
L
Amphipathic
Linear
Free
N[C@@H](CCCCN)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H]([C@@H](C)CC)C(=O)N[C@@H](CS)C(=O)N[C@@H]([C@@H](C)O)C(=O)N[C@@H](CCCN=C)C(=O)N[C@@H](CCCCN)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CCCN=C)C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H](CCSC)C(=O)N[C@@H](CO)C(=O)N[C@@H](C)C(=O)N[C@@H](CC1=CN=C(C)/C/1=C\C)C(=O)N[C@@H](C)C(=O)N[C@@H](CCC(=O)N)C(=O)O
Evidence Records 1 records
Evidence 1 Activity

Activity

Cell-penetrating Peptides

Target

By-2 Cells Leaves Of Nicotiana Benthamiana, Arabidopsis Thaliana, Tomato (Solanum Lycopersicum), Poplar (Hybrid Aspen Populus Tremula×Tremuloides Line T89), And Rice (Oryza Sativa).

Source & Reference

CPPsite3.0
CPPsite3

Other

Source Activity Label Source Definition
Cell-penetrating Peptides
CPPsite3.0 experimentally validated cell-penetrating peptide annotation.
Natural residues Linear L Amphipathic
TAMRA dye
In vitro
CCCCCCSSCSSHHHHC
Additional Detail Fields 1 fields
CCCCCCSSCSSHHHHC