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Peptide record

TPDB92963

KH9- OEP34 Cell-penetrating Peptides standard
28 amino acids
Basic Information
3D PDB MODEL
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TPDB92963
KH9- OEP34
Cell-penetrating Peptides
Delivery and barrier-penetrating peptides
CPPsite3.0
standard
No
A 28-aa standard natural cell-penetrating peptides peptide sequence curated from CPPsite3.0, with an available 3D structural model.
Chemical: Nanoparticles
Sequence
KHKHKHKHKHKHKHKHKHMFAFQYLLVM
Physicochemical Analysis
C170H262N56O31S2
RNDCEGIPSTW
HK
3650.43
11.08
18
0
9
+10
13.25
-1.632
41.79
Mammalian: 1.3 hour Yeast: 3 min E.coli: 2 min
1490
40.82
2
Residue Composition
number
1
A
0
R
0
N
0
D
0
C
0
E
1
Q
0
G
9
H
0
I
2
L
9
K
2
M
2
F
0
P
0
S
0
T
0
W
1
Y
1
V
Amino Acid Distribution
A: 1 R: 0 N: 0 D: 0 C: 0 E: 0 Q: 1 G: 0 H: 9 I: 0 L: 2 K: 9 M: 2 F: 2 P: 0 S: 0 T: 0 W: 0 Y: 1 V: 1
Chemical Descriptors
28
C170H262N56O31S2
3650.43
11.08
+10
13.25
-1.632
Free
Nanoparticles
L
Linear
Free
N[C@@H](CCCCN)C(=O)N[C@@H](CC1=NC=NC1)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CC1=NC=NC1)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CC1=NC=NC1)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](Cc1[nH]cnc1)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CC1=NC=NC1)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](Cc1[nH]cnc1)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](Cc1[nH]cnc1)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](Cc1[nH]cnc1)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](Cc1[nH]cnc1)C(=O)N[C@@H](CCCN=C)C(=O)N[C@@H](CCCN=C)C(=O)N[C@@H](CCCN=C)C(=O)N[C@@H](CCCN=C)C(=O)N[C@@H](CCCN=C)C(=O)N[C@@H](CCCN=C)C(=O)N[C@@H](CCCN=C)C(=O)N[C@@H](CCCN=C)C(=O)N[C@@H](CCCN=C)C(=O)O
Evidence Records 1 records
Evidence 1 Activity

Activity

Cell-penetrating Peptides

Target

Arabidopsis Thaliana (Arabidopsis Ecotype Col-0) , Soybean (Glycine Max) And Tomato (Solanum Lycopersicum)

Source & Reference

CPPsite3.0
CPPsite3

Other

Source Activity Label Source Definition
Cell-penetrating Peptides
CPPsite3.0 experimentally validated cell-penetrating peptide annotation.
Natural residues Linear L
Synthetic
Plasmid DNA
Chloroplast
The transfection efficiency of the clustered plasmid DNA/CTP/CPP complexes gradually increased (up to 7.6 times, 2.7 times in average) in Arabidopsis leaves at 24−72 h after spraying compared to plasmid DNA molecules or plasmid DNA/CTP complexes formed at N/P ratio = 1.0.
In vitro
CCSCCCCCCCGGGGSCCC
Additional Detail Fields 1 fields
CCSCCCCCCCGGGGSCCC