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Peptide record

TPDB92962

KH9- BP100 Cell-penetrating Peptides standard
29 amino acids
Basic Information
3D PDB MODEL
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TPDB92962
KH9- BP100
Cell-penetrating Peptides
Delivery and barrier-penetrating peptides
CPPsite3.0 MLCPP 2.0 Peptipedia PerseuCPP
standard
No
A 29-aa standard natural cell-penetrating peptides peptide sequence curated from CPPsite3.0, MLCPP 2.0, Peptipedia, and other sources, with an available 3D structural model.
Chemical: Nanoparticles
Sequence
KHKHKHKHKHKHKHKHKHKKLFKKILKYL
Physicochemical Analysis
C180H295N61O31
ARNDCEQGMPSTWV
K
3809.71
11.30
23
0
6
+15
18.44
-2.276
53.79
Mammalian: 1.3 hour Yeast: 3 min E.coli: 2 min
1490
39.11
1
Residue Composition
number
0
A
0
R
0
N
0
D
0
C
0
E
0
Q
0
G
9
H
1
I
3
L
14
K
0
M
1
F
0
P
0
S
0
T
0
W
1
Y
0
V
Amino Acid Distribution
A: 0 R: 0 N: 0 D: 0 C: 0 E: 0 Q: 0 G: 0 H: 9 I: 1 L: 3 K: 14 M: 0 F: 1 P: 0 S: 0 T: 0 W: 0 Y: 1 V: 0
Chemical Descriptors
29
C180H295N61O31
3809.71
11.30
+15
18.44
-2.276
Free
Nanoparticles
L
Cationic
Linear
Free
N[C@@H](CCCCN)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H]([C@@H](C)CC)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CC1=NC=NC1)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](Cc1[nH]cnc1)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](Cc1[nH]cnc1)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CC1=NC=NC1)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CC1=NC=NC1)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CC1=NC=NC1)C(=O)NCC(=O)N[C@@H](Cc1[nH]cnc1)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CC1=NC=NC1)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CC1=NC=NC1)C(=O)O.CCCCN
Evidence Records 1 records
Evidence 1 Activity

Activity

Cell-penetrating Peptides

Target

Arabidopsis Thaliana (Arabidopsis Ecotype Col-0) , Soybean (Glycine Max) And Tomato (Solanum Lycopersicum)

Source & Reference

CPPsite3.0
CPPsite3

Other

Source Activity Label Source Definition
Cell-penetrating Peptides
CPPsite3.0 experimentally validated cell-penetrating peptide annotation.
Natural residues Linear L Cationic
Fusogenic
Cyanine 3 (Cy3)-labeled pBI221
Cytoplasm
In tomato leaf cells, only KH9-BP100 demonstrated higher transfection efficiency of plasmid DNA molecules after spraying
In vitro
CCCHHHHHHHTSCSSSCCCC
Additional Detail Fields 1 fields
CCCHHHHHHHTSCSSSCCCC