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Peptide record

TPDB92958

PN509 (SEQ ID NO: 90) Cell-penetrating Peptides standard
36 amino acids
Basic Information
3D PDB MODEL
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TPDB92958
PN509 (SEQ ID NO: 90)
Cell-penetrating Peptides
Delivery and barrier-penetrating peptides
CellPPD CellPPD-MOD CPPsite3.0 MLCPP 2.0 Peptipedia PerseuCPP
standard
No
A 36-aa standard natural cell-penetrating peptides peptide sequence curated from CellPPD, CellPPD-MOD, CPPsite3.0, and other sources, with an available 3D structural model.
C-terminal: Amidation N-terminal: PEGylation
Sequence
KGSKKAVTKAQKKDGKKRKRSRKESYSVYVYKVLKQ-NH2
Physicochemical Analysis
C188H327N59O51
NCHIMFPW
K
4230.03
11.02
15
2
10
+13
15.96
-1.631
48.61
Mammalian: 1.3 hour Yeast: 3 min E.coli: 2 min
4470
105.67
10
Residue Composition
number
2
A
3
R
0
N
1
D
0
C
1
E
2
Q
2
G
0
H
0
I
1
L
12
K
0
M
0
F
0
P
4
S
1
T
0
W
3
Y
4
V
Amino Acid Distribution
A: 2 R: 3 N: 0 D: 1 C: 0 E: 1 Q: 2 G: 2 H: 0 I: 0 L: 1 K: 12 M: 0 F: 0 P: 0 S: 4 T: 1 W: 0 Y: 3 V: 4
Chemical Descriptors
36
C188H327N59O51
4230.03
11.02
+13
15.96
-1.631
Amidation
L
Linear
PEGylation
N[C@@H](CCCCN)C(=O)NCC(=O)N[C@@H](CO)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](C)C(=O)N[C@@H](C(C)C)C(=O)N[C@@H]([C@@H](C)O)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](C)C(=O)N[C@@H](CCC(=O)N)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CC(=O)O)C(=O)NCC(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCN=C)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCN=C)C(=O)N[C@@H](CO)C(=O)N[C@@H](CCCN=C)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCC(=O)O)C(=O)N[C@@H](CO)C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H](CO)C(=O)N[C@@H](C(C)C)C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H](C(C)C)C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](C(C)C)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCC(=O)N)C(=O)O
Evidence Records 1 records
Evidence 1 Activity

Activity

Cell-penetrating Peptides

Target

LacZ cells and murine taile fibroblast cells

Source & Reference

CPPsite3.0
CPPsite3
US 20060035815

Other

Source Activity Label Source Definition
Cell-penetrating Peptides
CPPsite3.0 experimentally validated cell-penetrating peptide annotation.
Natural residues Linear L
Synthetic
Nucleic acid (siRNA)
In vitro
CCCCSSCHHHHTTSCHHHHSCSCCCCCCCCCTTTCC
Additional Detail Fields 1 fields
CCCCSSCHHHHTTSCHHHHSCSCCCCCCCCCTTTCC