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Peptide record

TPDB92942

hLF-WT Cell-penetrating Peptides standard
22 amino acids
Basic Information
3D PDB MODEL
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TPDB92942
hLF-WT
Cell-penetrating Peptides
Delivery and barrier-penetrating peptides
CellPPD CellPPD-MOD CPPsite3.0 MLCPP 2.0 Peptipedia
standard
No
A 22-aa standard natural cell-penetrating peptides peptide sequence curated from CellPPD, CellPPD-MOD, CPPsite3.0, and other sources, with an available 3D structural model.
C-terminal: Amidation Chemical: Nanoparticle N-terminal: Acetylation
Sequence
Ac-KCFQWQRNMRKVRGPPVSCIKR-NH2
Physicochemical Analysis
C118H197N41O27S3
ADEHLTY
R
2718.30
11.98
7
0
6
+7
4.97
-1.041
44.09
Mammalian: 1.3 hour Yeast: 3 min E.coli: 2 min
5625
206.93
6
Residue Composition
number
0
A
4
R
1
N
0
D
2
C
0
E
2
Q
1
G
0
H
1
I
0
L
3
K
1
M
1
F
2
P
1
S
0
T
1
W
0
Y
2
V
Amino Acid Distribution
A: 0 R: 4 N: 1 D: 0 C: 2 E: 0 Q: 2 G: 1 H: 0 I: 1 L: 0 K: 3 M: 1 F: 1 P: 2 S: 1 T: 0 W: 1 Y: 0 V: 2
Chemical Descriptors
22
C118H197N41O27S3
2718.30
11.98
+7
4.97
-1.041
Amidation
Nanoparticle
L
Amphipathic
Linear
Acetylation
Evidence Records 1 records
Evidence 1 Activity

Activity

Cell-penetrating Peptides

Target

Mc3T3 And HeLa Cells

Source & Reference

CPPsite3.0
CPPsite3

Other

Source Activity Label Source Definition
Cell-penetrating Peptides
CPPsite3.0 experimentally validated cell-penetrating peptide annotation.
Non-natural residues Linear L Amphipathic
Protein derived
(Cy5)-labeled eGFP mRNA
Cytosol
hLF-WT , only little uptake and no expression were present
In vitro