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Peptide record

TPDB92891

H8 Cell-penetrating Peptides standard
8 amino acids
Basic Information
3D PDB MODEL
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TPDB92891
H8
Cell-penetrating Peptides
Delivery and barrier-penetrating peptides
CPPsite3.0
standard
No
A 8-aa standard natural cell-penetrating peptides peptide sequence curated from CPPsite3.0, with an available 3D structural model.
C-terminal: Amidation
Sequence
HHHHHHHH-NH2
Physicochemical Analysis
C48H58N24O9
ARNDCEQGILKMFPSTWYV
H
1115.14
8.30
8
0
0
+1
7.68
-3.200
0.00
Mammalian: 3.5 hour Yeast: 10 min E.coli: >10 hour
0
0.00
0
Residue Composition
number
0
A
0
R
0
N
0
D
0
C
0
E
0
Q
0
G
8
H
0
I
0
L
0
K
0
M
0
F
0
P
0
S
0
T
0
W
0
Y
0
V
Amino Acid Distribution
A: 0 R: 0 N: 0 D: 0 C: 0 E: 0 Q: 0 G: 0 H: 8 I: 0 L: 0 K: 0 M: 0 F: 0 P: 0 S: 0 T: 0 W: 0 Y: 0 V: 0
Chemical Descriptors
8
C48H58N24O9
1115.14
8.30
+1
7.68
-3.200
Amidation
L
Cationic
Linear
Free
N[C@@H](Cc1[nH]cnc1)C(=O)N[C@@H](CC1=NC=NC1)C(=O)N[C@@H](Cc1[nH]cnc1)C(=O)N[C@@H](CC1=NC=NC1)C(=O)N[C@@H](Cc1[nH]cnc1)C(=O)N[C@@H](Cc1[nH]cnc1)C(=O)O
Evidence Records 1 records
Evidence 1 Activity

Activity

Cell-penetrating Peptides

Target

Nicotiana Tabacum (Tobacco)By-2 Cells And S. Cerevisiae (Nmy51)

Source & Reference

CPPsite3.0
CPPsite3

Other

Source Activity Label Source Definition
Cell-penetrating Peptides
CPPsite3.0 experimentally validated cell-penetrating peptide annotation.
Natural residues Linear L Cationic
Synthetic
TAMRA-conjugated at N terminus
Vacuole
Internalized in both plant cells and yeast cells
Temperature-dependent endocytosis
In vitro
CCCCCC
Additional Detail Fields 1 fields
CCCCCC