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Peptide record

TPDB92874

LMWP-EGFP Cell-penetrating Peptides standard
16 amino acids
Basic Information
3D PDB MODEL
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TPDB92874
LMWP-EGFP
Cell-penetrating Peptides
Delivery and barrier-penetrating peptides
CPPsite3.0 Peptipedia
standard
No
A 16-aa standard natural cell-penetrating peptides peptide sequence curated from CPPsite3.0 and Peptipedia, with an available 3D structural model.
N-terminal: Conjugation with EGFP
Sequence
GSVSRRRRRRGGRRRR
Physicochemical Analysis
C77H150N46O19
ANDCEQHILKMFPTWY
R
2024.33
13.35
10
0
1
+10
8.46
-2.725
18.12
Mammalian: 30 hour Yeast: >20 hour E.coli: >10 hour
0
0.00
2
Residue Composition
number
0
A
10
R
0
N
0
D
0
C
0
E
0
Q
3
G
0
H
0
I
0
L
0
K
0
M
0
F
0
P
2
S
0
T
0
W
0
Y
1
V
Amino Acid Distribution
A: 0 R: 10 N: 0 D: 0 C: 0 E: 0 Q: 0 G: 3 H: 0 I: 0 L: 0 K: 0 M: 0 F: 0 P: 0 S: 2 T: 0 W: 0 Y: 0 V: 1
Chemical Descriptors
16
C77H150N46O19
2024.33
13.35
+10
8.46
-2.725
Free
L
Cationic
Linear
Conjugation with EGFP
NCC(=O)N[C@@H](CO)C(=O)N[C@@H](C(C)C)C(=O)N[C@@H](CO)C(=O)N[C@@H](CCCN=C)C(=O)N[C@@H](CCCN=C)C(=O)N[C@@H](CCCN=C)C(=O)N[C@@H](CCCN=C)C(=O)N[C@@H](CCCN=C)C(=O)N[C@@H](CCCN=C)C(=O)NCC(=O)NCC(=O)N[C@@H](CCCN=C)C(=O)N[C@@H](CCCN=C)C(=O)N[C@@H](CCCN=C)C(=O)N[C@@H](CCCN=C)C(=O)O
Evidence Records 1 records
Evidence 1 Activity

Activity

Cell-penetrating Peptides

Target

The mouse macrophage J774 A.1 cells

Assay & Model

Zebrafish
Zebrafish

Source & Reference

CPPsite3.0
CPPsite3

Other

Source Activity Label Source Definition
Cell-penetrating Peptides
CPPsite3.0 experimentally validated cell-penetrating peptide annotation.
Natural residues Linear L Cationic
Protein derived
Protein (eGFP)
Cytoplasm and nucleus
Transported EGFP into the Cytoplasm in great amount and even into the nucleus partly.
In vitro and in vivo
CCCCTTCSSCCCCCCC
Additional Detail Fields 1 fields
CCCCTTCSSCCCCCCC